308-nm Excimer Laser: a Hopeful and Optional Therapy for Pityriasis Versicolor.

This study aimed to evaluate the efficacy of excimer laser (308 nm) as an alternative therapy for PV.MATERIALS AND METHODS: This is a prospective intra-patient left-to-right, randomized, placebo-controlled study conducted on 26 patients with bilateral lesions which are not responding to the PV standard treatment. Patients were randomly assigned to right or left-side therapy for a duration of 8 weeks with either excimer laser (308 nm three times weekly) or topical placebo. Clinical assessment and mycological evaluation were performed before the initiation of treatment and at the 4th and 8th week of therapy.RESULTS: A decrease in the mean clinical score of cases was recorded from 7.1 at the baseline evaluation to 1.56 after 4 weeks and to 1.96 after 8 weeks of treatment. At week 4, there was a statistically significant reduction in the clinical scores compared with pre-treatment scores and with the placebo group (p
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research

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K Vichitra, Lokeshwari Gopal, Balajee Govindarao, V Chandrasekaran, Anupma Jyoti KindoIndian Journal of Medical Microbiology 2019 37(3):454-456 Post-renal transplant fungal infections continue to be a major cause of mortality and morbidity. Universally reported fungi are Candida, especially Candida albicans, Cryptococcus, Aspergillus, Trichophyton rubrum and Pityriasis versicolor. Here, we report a case of infection caused by a rare fungus Diaporthe. It is an endophyte reported as plant pathogens and infrequently in humans and mammals. The patient was a renal transplant recipient on immunosuppressant. He had hypothyroidis...
Source: Indian Journal of Medical Microbiology - Category: Microbiology Authors: Source Type: research
Conclusions: Our study revealed that toenail onychomycosis remains the most common superficial mycosis and T. rubrum is the most common pathogen. However, in a longer period of observation, a decrease in the number of tinea capitis cases and an increase in infections caused by T. tonsurans were noticed. Observed changes indicate the need for continuing studies to detect the upcoming epidemiological trends. PMID: 31839778 [PubMed]
Source: Advances in Dermatology and Allergology - Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research
AbstractPurpose of ReviewPityriasis versicolor (PV) is a superficial mycosis that it can occur at any age, even in newborns. In this review, we will describe epidemiological data, mycological characteristics of yeast, pathogenesis and clinical characteristics of the disease, different diagnostic resources, and the current recommendations for treatment.Recent FindingsThe typical morphology and topography of PV allow us to make a quick diagnosis, but atypical presentations have been described. Diagnostic tools, such as dermoscopy, can also reveal patterns that allow the evaluation of characteristics of scales and pigment in ...
Source: Current Fungal Infection Reports - Category: Infectious Diseases Source Type: research
Pityriasis versicolor (PV) is a common chronic superficial fungal infection of the skin caused by an unusual increased proliferation of Malassezia species in the stratum corneum layer of skin. Malassezia is a yeast that is part of the skin ’s habitual flora and it acquires a pathogenic potential when assuming the mycelial form under the influence of trigger factors including, humidity, immunosuppression, and hyperhidrosis. Systemic therapies are recommended for severe or recalcitrant cases, but they could come with important side ef fects and drug interactions.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Photobiology and Pigmentation Source Type: research
This article aims to review the literature on topical KTZ's efficacy and adverse effects, as well as provide an overview on current insights regarding its mechanism of action and upcoming developments. METHODS: A PubMed search was done to include randomized-controlled trials focusing on the use of topical KTZ on human subjects. RESULTS: Forty studies with 4566 patients were included in this review. Topical KTZ is clinically effective for the treatment of Malassezia-related conditions such as seborrheic dermatitis and pityriasis versicolor with a reported efficacy of 63-90% and 71-89%, respectively. DISCUSSION: ...
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research
AbstractPurpose of ReviewTo address the latest treatments used for pityriasis versicolor and identify those that have proven to be effective in recent publications.Recent FindingsEven thoughMalassezia spp. have shown resistance to antifungals, classical treatments continue to be effective, and other novelty therapies including light therapies have shown promising results in the treatment of this condition.SummaryPityriasis versicolor is a common superficial fungal infection of the skin. There are numerous and diverse topical and systemic therapeutic options that are successful for the treatment and prophylaxis of this myco...
Source: Current Fungal Infection Reports - Category: Infectious Diseases Source Type: research
Discussion During growth, plants first store their energy as carbohydrates but during ripening switch over to carbon-rich triglycerides. Triglycerides also occur in yeasts, molds and animal fats. A few higher plants store lipids in other forms. One example is the Jojoba which stores its oil as a lipid wax. Simmondsia chinensis (Jojoba) is a specialty-cultivated plant found mainly in the American Southwest and Mexican Northwest. Jojoba seed oil has> 50% of its weight as liquid wax esters that are used in personal care products and lubricants. Jojoba oil is naturally extracted from the seed or synthetically produced. Natu...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
AbstractThe increasing incidence of fungal infections and antifungal resistance has prompted the search for novel antifungal drugs and alternative agents. We explored the antifungal activity of Myrtus communis essential oil (EO) againstMalassezia sp. isolated from the skin of patients with pityriasis versicolor. These broad-spectrum antimicrobial activities ofM. communis EO and its potent inhibiting activity onMalassezia growth deserve further research with aim to considerate this EO as candidate for topical use in treatment of skin diseases.
Source: Infection - Category: Infectious Diseases Source Type: research
Pityriasis versicolor is a superficial fungal infection caused by Malassezia spp. The aim of this study is to propose the definition of a new clinical entity: the recurrent and disseminated pityriasis versicolor (RDPV). All patients with RDPV were enrolled over an eight-month period. Clinical and epidemiological data were obtained, Malassezia (M.) species were isolated in cultures and identified by phenotypic and molecular characterization, skin biopsies were taken from active lesions, serum levels of immunoglobulin E were obtained and therapeutic schemes were evaluated.
Source: Medical Hypotheses - Category: Biomedical Science Authors: Source Type: research
or mycoses are common treatable conditions seen in everyday clinical practice, although they can present differently in immunosuppressed patients. Dermatophyte or ringworm infections, superficial candidiasis of the mouth, skin or genital tract and infections caused by Malassezia, such as pityriasis versicolor, are the main conditions. Although they present with typical clinical changes, diagnosis can generally be confirmed by direct microscopy or culture of suitable samples.
Source: Medicine - Category: Internal Medicine Authors: Tags: Skin and soft tissue infections Source Type: research
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