Fetal Hypertension

Bassily et al1 describe significant risk factors in an obstetrical history with subsequent cardiovascular risk, including low birthweight, pre-eclampsia, gestational diabetes, and preterm labor. Moreover, there is the inference in the “fetal origins of adult disease” hypothesis that the pregnant mother “transmits” hypertension to her unborn child through “fetal programming” or “(epi)genomic” mechanisms.2 We believe that this “transmission” does take place through histologic evidence in the first few centimeter s of the fetal end of the umbilical cord.
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Letter Source Type: research

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BackgroundExtended embryo culture has been reported to affect perinatal outcome regarding higher risks of large for gestational age (LGA) and preterm birth (PTB) yet decreased risk of small for gestational age (SGA). However, existing data about the obstetric outcome and the safety for offspring resulting from the transfer of day 7 blastocysts is rare.ObjectivesTo compare obstetric and perinatal outcome using embryos vitrified on day 7 with those vitrified on day 3, day 5, and day 6.MethodsData were collected from 4489 infertile women who gave birth to live-born singletons after vitrified-warmed embryo transfer cycles from...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Obesity is a risk factor for pregnancy-induced hypertension (PIH), Pre-Eclampsia (PE), Gestational Diabetes Mellitus (GDM) and Large Gestational Age (LGA) pregnancy. Bariatric surgery is widely accepted to treat obesity but associated with small for gestational age (SGA) fetuses.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Tags: Original articles Source Type: research
CONCLUSION: In a large cohort of nulliparous women, more acculturation, regardless of self-described race or ethnicity, was associated with increased odds of several adverse pregnancy outcomes. CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, NCT01322529. PMID: 31923068 [PubMed - as supplied by publisher]
Source: Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Obstet Gynecol Source Type: research
Publication date: December 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 8Author(s): Alexandra Pouliot, Riham Elmahboubi, Catherine AdamAbstractObjectivesAt 1 Canadian university hospital, pregnant women were routinely screened for gestational diabetes mellitus (GDM) with a 75-g oral glucose tolerance test (OGTT). Diagnostic plasma glucose thresholds were as follows: fasting: ≥5.3 mmol/L, 1 h: ≥10.6 mmol/L and 2 h: ≥9.0 mmol/L. In 2015, diagnostic thresholds were reduced to those recommended by the International Association of Diabetes in Pregnancy Study Group (IADPSG) as follows: fasting: ≥5.1 mmo...
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
ConclusionBreech presentation in preterm labor is associated with obstetric risk factors compared to cephalic presentation. These risks decrease linearly with the gestational age. In moderate to late preterm delivery, breech presentation is a high-risk state and some obstetric risk factors are yet visible in early preterm delivery. Breech presentation in extremely preterm deliveries has, with the exception of preterm premature rupture of membranes, similar clinical risk profiles as in cephalic presentation.
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
Regular exercise is important to maintain health and reduce the risk of chronic disease in the general population. The greatest health benefits occur in sedentary individuals who incorporate small amounts of activity into their daily routine. Additional benefits of exercise for pregnant women include reduced rates of maternal and fetal complications, such as pre-eclampsia, gestational hypertension, gestational diabetes, Caesarean section, excessive gestational weight gain, and macrosomia.1 The trial of supervised moderate to vigorous prenatal exercise by Mireia Pelaez and colleagues,2 published in this issue of Mayo Clinic...
Source: Mayo Clinic Proceedings - Category: Internal Medicine Authors: Tags: Editorial Source Type: research
This study aims to determine the incidence of pre-eclampsia and distribution of risk factors of pre-eclampsia at Paropakar Maternity and Women’s Hospital, Kathmandu, Nepal. A retrospective study included 4820 pregnant women from 17 September to 18 December 2017. Data were obtained from the medical records of the hospital’s Statistics Department. Associations between the risk factors and pre-eclampsia were determined using logistic regression analysis and expressed as odds ratios. The incidence rate of pre-eclampsia in the study population was 1.8%. Higher incidence of pre-eclampsia was observed for wome...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Objectives: Either maternal gestational diabetes mellitus (GDM) or hypertensive disorder of pregnancy (HDP) is associated with an increased risk of obesity in the offspring. However, their joint associations with obesity in offspring remain unclear. We investigated the joint associations of maternal GDM and HDP with childhood overweight in offspring.Methods: We performed a large study in 1967 mother-child pairs. Maternal GDM was diagnosed according to the 1999 World Health Organization (WHO) criteria. HDP was defined as self-reported doctor-diagnosed hypertension or treatment of hypertension (including gestational hyperten...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Abstract Polycystic ovary syndrome (PCOS) is a prevalent hormonal disorder of premenopausal women worldwide and is characterized by reproductive, endocrine, and metabolic abnormalities. The clinical manifestations of PCOS include oligomenorrhea or amenorrhea, hyperandrogenism, ovarian polycystic changes, and infertility. Women with PCOS are at an increased risk of suffering from type 2 diabetes; me\tabolic syndrome; cardiovascular events, such as hypertension, dyslipidemia; gynecological diseases, including infertility, endometrial dysplasia, endometrial cancer, and ovarian malignant tumors; pregnancy complication...
Source: Reproductive Biology - Category: Reproduction Medicine Authors: Tags: Reprod Biol Endocrinol Source Type: research
Background: Women who experience complications of pregnancy including pre-eclampsia, hypertension and diabetes are at increased risk of coronary artery disease (CAD). Yet patients and their medical providers have low awareness of the significance of ‘non-traditional’ cardiovascular risk factors. We aimed to determine the prevalence and awareness of pregnancy-related vascular complications in women with known CAD.
Source: Heart, Lung and Circulation - Category: Cardiology Authors: Tags: 673 Source Type: research
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