Serum aflatoxin B1M1 and hepatocellular carcinoma in post-hepatitis C virus-infected Egyptian patients

Objectives Hepatitis C virus (HCV) chronically infected patients occur in about 3% of the world population with an increased risk to developing liver cirrhosis and cancer. Aflatoxin B1 (AFB1), a known human carcinogen, has a synergistic effect on HCV-induced hepatocellular carcinoma (HCC). We aimed to evaluate the association between AF B1M1 serum level and HCC in post-HCV-infected Egyptian patients. Patients and methods Group I: 25 HCV-infected patients with HCC; group II: 25 HCV-infected patients without HCC, as well as control group of 25 healthy individuals. Results Serum levels of α fetoprotein (AFP) and AFM1 were highly significant in group I than in group II and the control group (P
Source: Egyptian Liver Journal - Category: Gastroenterology Tags: Original articles Source Type: research