Physical Activity Compared to Adiposity and Risk of Liver-Related Mortality: Results from Two Prospective, Nationwide Cohorts

This is the first large, prospective cohort study to simultaneously evaluate the impact of obesity and physical activity on the long-term risk of liver-related mortality, in two nationwide populations of U.S. men and women. The study demonstrated that obesity predicted significantly increased risk of liver-related mortality, while physical activity predicted significantly lower risk of liver-related mortality. Importantly, the excess risk of liver-related mortality observed with obesity was no longer statistically significant among adults who engaged in the equivalent of average-pace walking for 3 hours or more, per week.

Source: Journal of Hepatology - January 14, 2020 Category: Gastroenterology Authors: Tracey G. Simon, Mi Na Kim, Xiao Luo, Wanshui Yang, Yanan Ma, Dawn Q. Chong, Charles S. Fuchs, Jeffrey A. Meyerhardt, Kathleen E. Corey, Raymond T. Chung, Meir Stampfer, Xuehong Zhang, Edward L. Giovannucci, Andrew T. Chan Source Type: research