GABAergic abnormalities in the fragile X syndrome.

In conclusion, there can be little doubt that the GABAergic system is compromised in the fragile X syndrome and that these abnormalities contribute to the clinical abnormalities observed. However, at the moment the difference in treatment effectiveness of agonist of the receptor in animal models as opposed to in patients remains unexplained. PMID: 31926845 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31926845?dopt=Abstract

Source: European Journal of Paediatric Neurology - December 23, 2019 Category: Neurology Authors: Van der Aa N, Kooy RF Tags: Eur J Paediatr Neurol Source Type: research