Characteristics and Outcomes of Patients Presenting With hypertensive urgency in the Office Setting: The Campania Salute Network.

Characteristics and Outcomes of Patients Presenting With hypertensive urgency in the Office Setting: The Campania Salute Network. Am J Hypertens. 2020 Jan 13;: Authors: Mancusi C, Losi MA, Albano G, De Stefano G, Morisco C, Barbato E, Trimarco B, De Luca N, de Simone G, Izzo R Abstract BACKGROUND: Hypertensive urgencies (HypUrg) are define as severe elevation in blood pressure (BP) without acute target organ damage (TOD). In the office setting, treated asymptomatic patients, with severe BP elevation meeting criteria for urgency are often seen. We evaluate incident CV events (fatal and non-fatal stroke or acute myocardial infarction, TIA, coronary or carotid revascularization, atrial fibrillation (n=311)) during follow-up (FU) in patients with HypUrg at first outpatient visit. METHODS: From the Campania Salute Network (CSN) Registry. HypUrg was define by systolic BP ≥180mmHg and/or diastolic BP ≥110mmHg. Patients were> 18 years old, with available ultrasound data, without prevalent CV disease and no more than stage III Chronic Kidney Disease. BP control was defined as the average BP during FU
Source: American Journal of Hypertension - Category: Cardiology Authors: Tags: Am J Hypertens Source Type: research

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Authors: Merrigan SL, Park B, Ali Z, Jensen LD, Corson TW, Kennedy BN Abstract Aberrant ocular angiogenesis can underpin vision loss in leading causes of blindness, including neovascular age-related macular degeneration and proliferative diabetic retinopathy. Current pharmacological interventions require repeated invasive administrations, may lack efficacy and are associated with poor patient compliance and tachyphylaxis. Vitamin D has de novo anti-angiogenic properties. Here, our aim was to validate the ocular anti-angiogenic activity of biologically active vitamin D, calcitriol, and selected vitamin D analogue, 2...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
Publication date: January 2020Source: Pregnancy Hypertension, Volume 19Author(s): Sarah Novotny, Nicole Lee-Plenty, Kedra Wallace, Wondwosen Kassahun-Yimer, Aswathi Jayaram, James A. Bofill, James N. MartinAbstractObjectiveTo determine the prevalence of acute kidney injury (AKI), placental abruption and postpartum hemorrhage in patients with preeclampsia or HELLP syndrome.Study designA retrospective study of patients with preeclampsia or HELLP syndrome treated at the University of Mississippi Medical Center from January 2000 through December 2010.Main outcome measuresRelationships among the obstetric complications of place...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
Publication date: January 2020Source: Pregnancy Hypertension, Volume 19Author(s): Laura A Magee, Joel Singer, Terry Lee, Richard J McManus, Sarah Lay-Flurrie, Evelyne Rey, Lucy C Chappell, Jenny Myers, Alexander G Logan, Peter von DadelszenAbstractObjectiveTo examine the relationship between pregnancy outcomes and BP level and variability.DesignSecondary analysis of CHIPS trial data (Control of Hypertension In Pregnancy Study, NCT01192412).SettingInternational.Population or sampleWomen with chronic or gestational hypertension.MethodsBP measurement was standardised in outpatient clinics. Adjusted (including for allocated gr...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
Publication date: January 2020Source: Pregnancy Hypertension, Volume 19Author(s): Cecilia Villalain, Ignacio Herraiz, Borja Cantero, Soledad Quezada, Ana Lopez, Elisa Simón, Alberto GalindoAbstractObjectivesThe optimal timing for delivery in non-severe late-preterm (34 + 0–36 + 6 weeks) preeclampsia (PE) is uncertain. It is attempted to reach term pregnancy safely but current clinical and analytical parameters fail to determine which cases will develop severe features that require preterm delivery. We aim to establish if angiogenic biomarkers may identify cases that would benefit from ...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
Publication date: January 2020Source: Pregnancy Hypertension, Volume 19Author(s): Mohamed Rezk
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
In conclusion, our data suggests that progression to kidney disease might not be a major concern in women after preeclampsia within 18 years postpartum.
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
Publication date: January 2020Source: Pregnancy Hypertension, Volume 19Author(s): Zain Awamleh, Victor K.M. HanAbstractPreeclampsia (PE) and intrauterine growth restriction (IUGR) are pregnancy complications resulting from abnormal placental development. As epigenetic regulators, microRNAs can regulate placental development and contribute to the disease pathophysiology by influencing the expression of genes involved in placental development or disease. Our previous study revealed an increase in miR-210-5p expression in placentae from patients with early-onset pregnancy complications and identified candidate gene targets fo...
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
ConclusionWe feel these data are suggestive of increased on-aspirin platelet (re-)activity, as measured by the PFA-200 and the VerifyNow, in non-pregnant carriers of a FII-mutation, but not in carriers of FVL-mutation. Interestingly, this increased on-aspirin platelet (re-)activity is present in spite of low sTxB2 levels.
Source: Pregnancy Hypertension: An International Journal of Womens Cardiovascular Health - Category: OBGYN Source Type: research
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
"One-tenth of 50-year-old men have a heart age 10 years older than they are," BBC News reports. This is the finding of an analysis of 1.2 million people who used the NHS Heart Age Test. The principle behind the test is that you can "age" your heart through unhealthy behaviour such as smoking and being obese. Underlying conditions like high blood pressure and high cholesterol, which often have no noticeable symptoms, can also age the heart. An obese smoker in their 50s who has high blood pressure and high cholesterol could have the heart of a 60- or 70-year-old. The quick and simple test tells you the...
Source: NHS News Feed - Category: Consumer Health News Tags: Heart/lungs Source Type: news
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