Serious Adverse Events Cluster in Participants Experiencing the Primary Composite Cardiovascular Endpoint: A Post-Hoc Analysis of the SPRINT Trial.

Serious Adverse Events Cluster in Participants Experiencing the Primary Composite Cardiovascular Endpoint: A Post-Hoc Analysis of the SPRINT Trial. Am J Hypertens. 2020 Jan 13;: Authors: Botchway A, Buhnerkempe MG, Prakash V, Al-Akchar M, Adekola O, Flack JM Abstract BACKGROUND: Intensively treated participants in the SPRINT study experienced fewer primary cardiovascular composite study endpoints (CVD events) and lower mortality, although 38% of participants experienced a serious adverse event (SAE). The relationship of SAEs with CVD events is unknown. METHODS: CVD events were defined as either myocardial infarction, acute coronary syndrome, decompensated heart failure, stroke, or death from cardiovascular causes. Cox models were utilized to understand the occurrence of SAEs with CVD events according to baseline atherosclerotic cardiovascular disease (ASCVD) risk. RESULTS: SAEs occurred in 96% of those experiencing a CVD event but only in 34% (p
Source: American Journal of Hypertension - Category: Cardiology Authors: Tags: Am J Hypertens Source Type: research

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Source: International Urology and Nephrology - Category: Urology & Nephrology Source Type: research
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Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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Source: Reviews in Cardiovascular Medicine - Category: Cardiology Tags: Rev Cardiovasc Med Source Type: research
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Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
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Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
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Source: American Journal of Cardiovascular Drugs - Category: Cardiology Source Type: research
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Source: - Daily MedNews - Category: General Medicine Source Type: news
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Source: Circulation Research - Category: Cardiology Authors: Tags: Circ Res Source Type: research
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Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Original Research Article Source Type: research
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