Mesonephric-like adenocarcinomas of the uterine corpus: report of a case series and review of the literature indicating poor prognosis for this subtype of endometrial adenocarcinoma.

CONCLUSION: Uterine ML-AC represents a distinct subtype of invasive endometrial AC, associated with KRAS-mutations and characteristic immunohistochemical findings. Clinically, ML-AC may show an aggressive behavior with a high rate of recurrent disease and a substantial risk for distant metastatic disease, especially to the lungs.
PMID: 31927619 [PubMed - as supplied by publisher]

Source: Clinical Genitourinary Cancer - January 10, 2020 Category: Cancer & Oncology Authors: Horn LC, Höhn AK, Krücken I, Stiller M, Obeck U, Brambs CE Tags: J Cancer Res Clin Oncol Source Type: research