Moderate Levels of N-Terminal Pro-B-Type Natriuretic Peptide is Associated with Increased Risks of Total and Ischemic Strokes among Japanese: The Circulatory Risk in Communities Study.

CONCLUSION: We found that even moderate serum levels of NT-proBNP were associated with the risk of total and ischemic strokes among Japanese whose NT-proBNP levels were relatively low compared with Westerners. PMID: 31932552 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

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Authors: Chiba Y, Fukushima A, Nakao M, Kobayashi Y, Ishigaki T, Tenma T, Kamiya K, Shingu Y, Ooka T, Matsui Y, Anzai T Abstract A 23-year-old man had progressive muscle weakness and Emery-Dreifuss muscular dystrophy (EDMD) due to a LMNA (lamin A/C) mutation. Congestive heart failure diagnosed at 19 years of age. Maximal drug treatment/cardiac resynchronization failed to improve the cardiac function. He was therefore hospitalized due to heart failure. Despite extracorporeal membrane oxygenation, he developed severe right heart dysfunction and died (multiple organ failure). A cardiac lesion's presence determines the...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
Publication date: Available online 20 February 2020Source: Life SciencesAuthor(s): Mahsa Hassanipour, Mohammadreza Zarisfi, Vahid Ehsani, Mohammad AllahtavakoliAbstractLate treatment with tissue plasminogen activator (tPA) leads to reperfusion injury and poor outcome in ischemic stroke. We have recently shown the beneficial effects of local brain hypothermia after late thrombolysis. Herein, we investigated whether transient whole-body hypothermia was neuroprotective and could prevent the side effects of late tPA therapy at 5.5 h after embolic stroke. After induction of stroke, male rats were randomly assigned into four g...
Source: Life Sciences - Category: Biology Source Type: research
Publication date: Available online 20 February 2020Source: Fish &Shellfish ImmunologyAuthor(s): Sarithaa Sellaththurai, K.A.S.N. Shanaka, D.S. Liyanage, Hyerim Yang, Thanthrige Thiunuwan Priyathilaka, Jehee LeeAbstractMalectin is a carbohydrate-binding lectin protein found in the endoplasmic reticulum (ER). It selectivity binds to Glc2-N-glycan and is involved in a glycoprotein quality control mechanism. Even though malectin may play a role in immunity, its role in innate immunity is not fully known. In the present study, we identified and characterized the malectin gene from Hippocampus abdominalis (HaMLEC). We analyz...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
AbstractPharmaceuticals are widely detected in aquatic environments, and their potential risks to aquatic species are of concern because they are designed to be biologically active. Here, we used an in vitro assay, called the transforming growth factor α shedding assay, to measure the biological activities of G protein‐coupled receptor (GPCR)‐acting pharmaceuticals present in river water and effluents from municipal wastewater treatment plants (WWTPs) in Japan from 2014 to 2016. Antagonistic activities against angiotensin (AT1), dopamine (D2) , adrenergic (β1), acetylcholine (M1) and histamine (H1) receptors...
Source: Journal of Applied Toxicology - Category: Toxicology Authors: Tags: RESEARCH ARTICLE Source Type: research
WHO issues latest briefing; South Korean city sees surge in cases; and two Japanese passengers from stricken Diamond Princess ship dieSouth Korean city on high alert as cases soar at ‘cult’ churchExperts fear false rumours could harm China cooperation on virusBritons stuck on cruise ship to be flown homeShare your experiences3.52pmGMTThe World Health Organization is coordinating with the African Union to prepare the continent ’s countries for potential arrivals of people infected with coronavirus.Last week, the first case of coronavirus in Africa was confirmed when a case emerged in Egypt."We ’...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak China Japan Asia Pacific Infectious diseases Science World news Source Type: news
Publication date: March 2020Source: The Lancet Global Health, Volume 8, Issue 3Author(s): Jasper Tromp, Sahiddah Bamadhaj, John G F Cleland, Christiane E Angermann, Ulf Dahlstrom, Wouter Ouwerkerk, Wan Ting Tay, Kenneth Dickstein, Georg Ertl, Mahmoud Hassanein, Sergio V Perrone, Mathieu Ghadanfar, Anja Schweizer, Achim Obergfell, Carolyn S P Lam, Gerasimos Filippatos, Sean P CollinsSummaryBackgroundHeart failure is a global public health problem, affecting a large number of individuals from low-income and middle-income countries. REPORT-HF is, to our knowledge, the first prospective global registry collecting information o...
Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
Publication date: March 2020Source: The Lancet Global Health, Volume 8, Issue 3Author(s): Nitish Naik, Jagat Narula
Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
PURPOSE: The Japanese authorities require a 2-year seizure-free period for a driver's license in people with epilepsy. To evaluate the stringency of the criteria, we calculated the risk of fatal traffic crashes by epileptic seizure and compared that to the...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
OBJECTIVE To compare the deaths and injuries caused by road traffic accidents in China, Japan and Cambodia, and predict whether the three countries can achieve the goal set in the Sustainable Development Goals to reduce the number of road traffic deaths an...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Commentary Source Type: news
ConclusionHigh index of suspicion for thrombophilic disorders is required in postpartum patients presenting with respiratory distress as prompt diagnosis and urgent intervention can save patient’s life.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
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