Korean Red Ginseng suppresses bisphenol A-induced expression of cyclooxygenase-2 and cellular migration of A549 human lung cancer cell through inhibition of ROS

ConclusionsOverall, our results suggest that KRG exerts an anti-inflammatory effect on BPA-treated A549 cells via the suppression of ROS and down-regulation of NF-κB activation and COX-2 expression which leads to a decrease in cellular migration and MMP-9 expression. These results provide a new possible therapeutic application of KRG to protect BPA-induced possible inflammatory disorders.Graphical abstract
Source: Journal of Ginseng Research - Category: Complementary Medicine Source Type: research