KARAOKE: Krill oil versus placebo in the treatment of knee osteoarthritis: protocol for a randomised controlled trial

This study will provide high-quality evidence to assess whether krill oil 2  g/day reduces pain and effusion-synovitis size in older adults with clinical knee OA and knee effusion-synovitis. If krill oil is effective and confirmed to be safe, we will provide compelling evidence that krill oil improves pain and function, changes disease trajectory and slows disease progres sion in OA. Given the lack ofapproved therapies for slowing disease progression in OA, and moderate cost of krill oil, these findings will be readily translated into clinical practice.Trial registrationAustralian New Zealand Clinical Trials Registry,ACTRN12616000726459. Registered on 02 June 2016.Universal Trial Number (UTN) U1111 –1181-7087.
Source: Trials - Category: Research Source Type: clinical trials