ZC3H7B –BCOR high-grade endometrial stromal sarcoma may present as myoma nascens with cytoplasmic signet ring cell change

In conclusion, these findings further support the idea of routine reflex molecular testing of uterine mesenchymal tumors with unusual clinical presentation or in case malignancy is suspected. Lastly, we suggestZC3H7B –BCOR rearranged high-grade endometrial stromal sarcoma might be considered as a tumor suitable for BCL6-targeted treatment.

http://link.springer.com/10.1007/s00428-020-02744-5

Source: Virchows Archiv - January 13, 2020 Category: Pathology Source Type: research