Blastocyst collapse as an embryo marker of low implantation potential: a time-lapse multicentre study.

This study suggests that human blastocysts that collapse spontaneously during development are less likely to implant and generate a pregnancy compared with embryos that do not. Although this is a retrospective study, the results demonstrated the utility of collapse episodes as new marker of embryo selection following eSET at blastocyst stage. PMID: 31928572 [PubMed - as supplied by publisher]
Source: Zygote - Category: Reproduction Medicine Authors: Tags: Zygote Source Type: research

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Publication date: Available online 14 February 2020Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Maud D. van Zijl, Bouchra Koullali, Martijn A. Oudijk, Anita C.J. Ravelli, Ben W.J. Mol, Eva Pajkrt, Brenda M. KazemierAbstractObjectivePreterm birth is the most important cause of perinatal morbidity and mortality. Over the past years several preventive measures have been studied and implemented. Preterm birth percentage in 2015 in the Netherlands was 6.9%, according to data from the European Peristat project, reporting on perinatal health in Europe. Various preventive measures might...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Abstract The main aim of this prospective study was to investigate the effect of the concentration of fat-soluble vitamins A, D, E and K in individual follicles on oocyte quality and developmental competence. The analysis was performed on 313 follicular fluid (FF) samples from 50 patients undergoing ovarian stimulation with intracytoplasmic sperm injection. We demonstrated that the mean concentration of individual vitamins in FF correlated with their level in serum (p
Source: Systems Biology in Reproductive Medicine - Category: Reproduction Medicine Authors: Tags: Syst Biol Reprod Med Source Type: research
Thyroid, Ahead of Print.
Source: Thyroid - Category: Endocrinology Authors: Source Type: research
ConclusionBased on our results, social freezing in Germany may lead to additional pregnancies among women over 40 but also to significantly higher costs, since given the current live birth success rates and pricing, social freezing does not appear to be cost-effective.
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
A new study on how and when the precursors to eggs and sperm are formed during development could help pave the way for generating egg and sperm cells in the lab to treat infertility.The study, published in the journal Cell Reports, describes the way in which human stem cells evolve into germ cells, the precursors for egg and sperm cells.“Right now, if your body doesn’t make germ cells then there’s no option for having a child that’s biologically related to you,” said Amander Clark, the study’s lead author, a member of the Eli and Edythe Broad Center of Regenerative Medicine and Stem...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Conclusion: CHMCF may occur after ICSI treatment. Pregnancies with CHMCF are associated with severe complications however under close follow-up successful outcomes could be achieved in such pregnancies. PMID: 31997691 [PubMed - as supplied by publisher]
Source: Fetal and Pediatric Pathology - Category: Pathology Tags: Fetal Pediatr Pathol Source Type: research
Abstract Cancer is the second major cause of death in the world. The problem of post-cancer infertility plays a significant role, because chemotherapy can be gonadotoxic. Cryopreservation of ovarian tissue before cancer therapy with re-implantation after convalescence is the potential key solution to this problem. The aim of this study was to test the viability of cryopreserved human ovarian cortex after long-term cooling in culture medium composed of permeable cryoprotectants. Ovarian fragments from sixteen patients were randomly divided into two groups. After the operation, tissue pieces assigned to both groups ...
Source: Cryobiology - Category: Biology Authors: Tags: Cryobiology Source Type: research
Publication date: Available online 23 January 2020Source: Reproductive BioMedicine OnlineAuthor(s): Ryan D. Rose, Michael F. Barry, Emma V. Dunstan, Siu Man Yuen, Lyndal P. Cameron, Emma J. Knight, Robert J. Norman, Mary-Louise HullAbstractResearch QuestionDoes Embryogen®/BlastGen™ culture medium improve live birth rates compared to standard culture medium for women undergoing IVF/ICSI with poor prognosis.DesignRandomised clinical trial. 100 couples undergoing IVF/ICSI, were randomly allocated to having their inseminated oocytes incubated in either Embryogen®/BlastGen™ sequential culture media (Cooper S...
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
ConclusionsThe rate of successful TESE and the ICSI outcome in cancer survivors with NOA and RE/FOE is the same as non-cancer azoospermic patients. Female partner age (older than 40  years) was associated with a significant reduction in live birth rates after TESE-ICSI procedures.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research
ConclusionsThe quantity of TQBs available for transfer or cryopreservation can provide important predictors for pregnancy and live birth after the first embryo transfer cycle with a single blastocyst. This valuable information may assist with the future application of SBT.
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
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