The MBOAT7 rs641738 variant is associated with an improved outcome in primary sclerosing cholangitis.
CONCLUSIONS: Unlike other chronic liver diseases, carrying two MBOAT7 variant alleles does not seem to affect PSC patients negatively, but seems to have a positive effect on transplant-free survival. This study could help improve individual prognosis in PSC patients and give some new perspective on the involvement of the immune system in PSC.
PMID: 31928970 [PubMed - as supplied by publisher]
Source: Clin Med Res - Category: Research Authors: Freund C, Wahlers A, Begli NH, Leopold Y, Klöters-Plachky P, Mehrabi A, Mohr I, Sander J, Rupp C, Gotthardt DN, Weiss KH Tags: Clin Res Hepatol Gastroenterol Source Type: research
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