Thrombin as Key Mediator of Seizure Development Following Traumatic Brain Injury

In conclusion, these observations indicate a synergism between thrombin and mTBI in lowering seizure in the pilocarpine model and possibly aggravating inflammation. We believe that these results will improve the understanding of PTS pathophysiology and contribute to the development of more targeted therapies in the future.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research