Key Features Defining the Disposition of Bispecific Antibodies and Their Efficacy In Vivo

This study summarizes several PK and PD aspects that are specific for BsAbs and are important for the success of these new drugs. We emphasize previous PK/PD studies that have been fundamental for the correct prediction of appropriate dosages and schedules of these new drugs in clinical trials or for defining which drugs may take advantage of individualized and standardized drug monitoring for improved efficacy and safety.
Source: Therapeutic Drug Monitoring - Category: Drugs & Pharmacology Tags: Review Article Source Type: research