The association between atrial fibrillation and Alzheimer's disease: fact or fallacy? A systematic review and meta-analysis

Conclusion Pooled analysis suggest that patients with atrial fibrillation may be exposed to an increased risk of developing new onset of Alzheimer's disease. Given the relevant clinical implications, further studies are required to corroborate these findings.
Source: Journal of Cardiovascular Medicine - Category: Cardiology Tags: Research articles: Arrhythmias Source Type: research

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Whole organs are difficult to study in minute detail, as they have to be sliced into extremely thin sections to map out their interior. CT and magnetic resonance imaging help to an extent, but researchers at the Helmholtz Zentrum München, Ludwig...
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ConclusionsIn patients aged ≥ 85 years with moderate-severe dementia and AF, oral anticoagulation was significantly associated with a lower embolic risk and a higher bleeding risk, with no differences in total mortality.ResumenIntroducción y objetivosEl envejecimiento de la población se asocia con una prevalencia creciente de fibrilación auricular (FA) y demencia. Con este estudio se pretende analizar el impacto de la anticoagulación oral en pacientes ancianos con FA y demencia de grado moderado-grave.MétodosEstudio retrospectivo unicéntrico que analiza a pacientes de edad ≥&...
Source: Revista Espanola de Cardiologia - Category: Cardiology Source Type: research
Multiple occupational therapy sessions, provided in a person with dementia's own home, improve their ability to carry out daily activities, compared with usual care. Improvements are also seen in behavioural and psychological symptoms and their quality of life. In addition, carers report feeling less distress, and a better quality of life.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
Publication date: Available online 17 February 2020Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Zhike Zhou, Yifan Liang, Xiaoqian Zhang, Junjie Xu, Jueying Lin, Rongwei Zhang, Kexin Kang, Huiling Qu, Chuansheng Zhao, Mei ZhaoAbstractBackgroundThe aim of this meta-analysis is to evaluate the association of fibrinogen with risk of dementia and its subtypes.MethodsEmbase, Pubmed and Web of Science were retrieved systematically up to February 2019. Standard mean difference (SMD) with 95% confidence intervals was estimated using random-effects models.ResultsSixteen studies involving 3,649 participants were summariz...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
In conclusion, taller body height at the entry to adulthood, supposed to be a marker of early-life environment, is associated with lower risk of dementia diagnosis later in life. The association persisted when adjusted for educational level and intelligence test scores in young adulthood, suggesting that height is not just acting as an indicator of cognitive reserve. Link: https://doi.org/10.7554/eLife.51168
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
When PET scans reveal elevated amyloid levels in cognitively normal older adults,...Read more on AuntMinnie.comRelated Reading: FDG-PET shows where exercise could stall Alzheimer's PET, MRI link amyloid plaque with swift decline Who should get brain scans for Alzheimer's disease? PET, MRI show physical activity aids brain health Would high amyloid level spur physician-assisted death?
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(University of California - Irvine) Low oxygen levels in the heart have long been known to produce life-threatening arrhythmias, even sudden death. Until now, it was not clear how. New findings, in a study led by Steve A. N. Goldstein, MD, PhD, vice chancellor for Health Affairs at the University of California, Irvine, and distinguished professor in the UCI School of Medicine Departments of Pediatrics and Physiology&Biophysics, reveal the underlying mechanism for this dangerous heart disorder.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
(Alzheimer Europe) Today, at a European Parliament lunch debate, Alzheimer Europe launched a new report presenting the findings of its collaborative analysis of recent prevalence studies and setting out updated prevalence rates for dementia in Europe. The report findings show that, despite a marked reduction in the prevalence of dementia, the number of people with dementia is nonetheless set to double by 2050.
Source: EurekAlert! - Social and Behavioral Science - Category: International Medicine & Public Health Source Type: news
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
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Authors: Jacobs V, Graves KG, Bunch TJ Abstract INTRODUCTION: Atrial fibrillation (AF) is strongly associated with dementia, including idiopathic dementias such as Alzheimer's disease. The relative risk of dementia is highest in AF patients 70 years and younger, and the burden of exposure to arrhythmia appears to underlie part of the risk. Areas covered: Anticoagulation choices and approach influence dementia risk. In warfarin patients, inadequate time spent in therapeutic range is highly associated with the increased dementia risk long-term. This risk is further accentuated with frequent over anticoagulation in pa...
Source: Expert Review of Cardiovascular Therapy - Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research
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