Patterns of care for patients with non-operable T1-4 N+ M0 non-small cell lung cancer in the US and outcomes with radiation or chemotherapy monotherapies

Treatment of patients with inoperable locally advanced non-small cell lung cancer (NSCLC), defined as lymph node-positive (N+) non-metastatic (M0), has improved tremendously since the first trial comparing radiation monotherapy (RTmono) to placebo [1]. Randomized trials established concurrent chemoradiation (CRT) as the standard of care for non-operable N  + M0 NSCLC [2–4]. However, in practice patients are excluded from this regimen because of a poor performance status, limited social support system, or patient refusal [5,6].

Source: Lung Cancer - January 12, 2020 Category: Cancer & Oncology Authors: Ellen Kim, Megan E. Daly, Kenneth Westover, Timur Mitin Source Type: research