Combination Cancer Therapy is Focus of $1M Merck Research Grant Received by NCCN
NCCN has been awarded a $1M research grant from Merck &Co, Inc., that will support research of the anti-cancer agent vorinostat (Zolinza®). Vorinostat is currently used to treat progressive, persistent, or recurrent cutaneous T-cell lymphoma. This research grant will fund studies to explore the efficacy of vorinostat in combination with chemotherapy and/or radiation therapy in selected locally advanced non-metastatic cancers including non-small cell lung cancer, head and neck cancer, panc...
Joanna Smith, 58, of Clapham, Bedfordshire, first realised something was wrong when she spotted a tiny 'ulcer' in her mouth in October last year, which then grew and became painful.
Fabio Penna, Riccardo Ballar ò, Marc Beltrà, Serena De Lucia, Lorena García Castillo, Paola Costelli
People with a history of smoking have less effective immune system, study at University of Leeds showed. Researchers stressed the importance of quitting after a diagnosis.
CANCER symptoms: There are over 200 types of cancer and symptoms vary between the different types. However, some symptoms overlap and there are a few tell-tale signs everyone should be aware of. Here are six signs signalling the disease that always require a visit to the doctor.
Conclusions: Our data showed that PAA with TAZ/PIPC with a shorter duration PAA (48 h) might be recommended for RC with urinary diversion. We found that the surgical time was significantly shorter in the non-infection group. A prospective study based on our data is desirable to establish or revise PAA strategy for prophylactic medication to prevent postoperative infection after RC with urinary diversion.Urol Int
We examined two types of hepatocellular carcinoma- typical and fibrolamellar one. Our analysis revealed that DLC2 protein is not diminished in cancer tissue when compared to non-cancerous liver specimens. What is more, we observed DLC2 to be more abundantly expressed in cancer tissue, particularly in tumors with the inflammation background. In addition, we found thatDLC2 gene status was diploid in virtually all tumor samples examined. Our results indicate that DLC2 is not diminished in hepatocellular carcinoma cells. It appears that members of the DLC family, although structurally highly related, may function differently in cancer cells.
Philips Healthcare is launching a new mobile C-arm called Zenition that brings...Read more on AuntMinnie.comRelated Reading: Philips upgrades IntelliSpace Cardiovascular Philips adds to health informatics platform Philips, MIM to collaborate on radiation therapy IGT, ultrasound sales growth propel Philips sales in Q4 Philips debuts upgrade to Azurion angiography platform
Evidence suggests that breast cancer survivors are at risk for anxiety, depression, and suicide.Journal of the National Cancer Institute
How do dietary patterns impact the risk of developing colorectal cancer? This meta-analysis summarizes current evidence regarding the complex relationship between diet and colorectal cancer.Current Opinion in Gastroenterology
Authors: Shen D, Yu X, Wu Y, Chen Y, Li G, Cheng F, Xia L Abstract INTRODUCTION: Retinoic acid X receptors play key roles in tumor cell proliferation, differentiation, apoptosis and angiogenesis via transcriptional regulation. Bexarotene is a specific RXRs agonist which has been granted by FDA approval for the clinical treatment of cutaneous T cell lymphoma (CTCL). Its cancer prevention and treatment potentials in various tumors have been under investigation over the past decade. Areas covered: This review summarizes the efficacy and underlying mechanisms of bexarotene for the treatment of multiple cancers based on...