The novel sophoridine derivate IMB-HDC induced lessened phosphorylation of STAT5a at 694 and 780 and promoted DNA breakage and cell apoptosis via blocking STAT5a nuclear translocation

Acta Pharmacologica Sinica, Published online: 13 January 2020; doi:10.1038/s41401-019-0333-6The novel sophoridine derivate IMB-HDC induced lessened phosphorylation of STAT5a at 694 and 780 and promoted DNA breakage and cell apoptosis via blocking STAT5a nuclear translocation

Source: Acta Pharmacologica Sinica - January 12, 2020 Category: Drugs & Pharmacology Authors: Wu-li Zhao Yan Xing Cheng Ye Yu-han Qiu Yi Li Xiu-jun Liu Meng-yan Wang Chong-wen Bi Dan-qing Song Rong-guang Shao Source Type: research