Urinary tract infections in children & lt;  2 years of age hospitalized in a tertiary medical center in Southern Israel: epidemiologic, imaging, and microbiologic characteristics of first episode in life

The objectives of the study were to describe the epidemiologic, microbiologic, and imaging characteristics of first 44 UTI episode in hospitalized infants and children<  2 years of age. A UTI episode was diagnosed based on suprapubic aspiration or urinary catheterization and report of a significant bacterial growth of true uropathogens. Two thousand two hundred ninety-four UTI episodes were recorded during 2009–2013 in 1694 patients; 1350 (79.7%), 223 (13.2%), and 66 (3.9%) had one, two, and three episodes, respectively. Of 1955 pathogens isolated, the most frequent wereE. coli,Klebsiella spp., andEnterococcus spp. (56.9%, 14.1%, and 11%, respectively).E. coli percentages increased with increase in patient age whileKlebsiella spp. andEnterococcus spp. decreased with decrease in age. 136/344 (39.5%) renal ultrasound examinations performed were reported abnormal. The percentages of abnormal ultrasound examinations inEnterococcus spp.-UTI were higher than inE. coli andKlebsiella spp.-UTI (P <  0.001 andP = 0.007, respectively). TheE. coli nonsusceptibility to ampicillin, TMP/SMX, ceftriaxone, amoxicillin/clavulanic acid, cefuroxime, and gentamicin was 71%, 31%, 14.9%, 14.7%, 7%, and 4.4%, respectively. Nonsusceptibility ofKlebsiella spp. to ampicillin, amoxicillin/clavulanic acid, TMP/SMX, ceftriaxone, gentamicin, and cefuroxime was 98.7%, 10.4%, 9.5%, 8.4%, 4.8%, and 4.3%, respectively.E. coli nonsusceptibility to amoxicillin/clavulanate, TMP/SMX, and ciproflo...
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research