Conversion to Positive Latent Tuberculosis Infection Status is Low in Hidradenitis Suppurativa Patients Taking Biologic Medications

Source: Journal of the American Academy of Dermatology - Category: Dermatology Authors: Source Type: research

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Discussion Hidradenitis suppurativa (HS) is a recurrent, chronic inflammatory disease of the hair follicles particularly in the apocrine gland-bearing areas of the axilla, inguinal, perianal, mammary and inframammary areas. Onset is usually after puberty, in the early 20s. It is more common in females than males. Prevalence is estimated to be 0.05- 4.1%. It can be associated with premature adrenarche, metabolic syndrome and obesity. The lesions are often pruritic, painful, and with malodorous purulent drainage. It often begins with comedomes and tender nodules, and can easily progress to painful abscesses with purulent f...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
This article is protected by copyright. All rights reserved. PMID: 30281779 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research
We report a case ofClostridium difficile infection in a patient with hidradenitis suppurativa who was taking clindamycin and rifampin.Clostridium difficile infection treatment prompted discontinuation of the medication.Clostridium difficile infection is known to develop after antibiotic treatment, such as clindamycin, but has rarely been associated with anti-tuberculosis agents, such as rifampin. Clinicians should be aware of the risk ofClostridium difficile infection in patients with hidradenitis suppurativa, even in those receiving rifampin.
Source: Dermatology Online Journal - Category: Dermatology Source Type: research
Authors: Boortalary T, Misra K, McNish S, Jones D, Shanmugam VK Abstract Hidradenitis suppurativa (HS) is a chronic, recurrent, inflammatory disease of the apocrine sweat glands. Tumor necrosis factor-alpha (TNF-α) inhibitors are commonly used to treat HS. However, prior to initiating therapy patients must be screened for mycobacterium tuberculosis (mTB) exposure. Several mTB screening tests based on interferon gamma release assays are commercially available, but the performance of these assays in the HS population is unknown. The purpose of this study was to investigate the performance of the QuantiFERON gol...
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research
Source: British Journal of Dermatology - Category: Dermatology Authors: Tags: Letter to the Editor Source Type: research
This article is protected by copyright. All rights reserved.
Source: British Journal of Dermatology - Category: Dermatology Authors: Tags: Letter to the Editor Source Type: research
This article is protected by copyright. All rights reserved.
Source: British Journal of Dermatology - Category: Dermatology Authors: Tags: Research Letters Source Type: research
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