Does longer sevoflurane preconditioning contribute to better neuroprotective effects?

Sevoflurane belongs to volatile anesthetics, and preconditioning with sevoflurane has been shown to exert protective effects against ischemic injury in the brain. But the mechanism is unclear. Although studies have shown the neuroprotective effects of sevoflurane preconditioning in the transient cerebral ischemia model, its effect in the permanent focal cerebral ischemia model remains unclear. Dr...
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Neurology / Neuroscience Source Type: news

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Conclusions: Operative laparoscopy under conscious sedation and local anesthesia appears to be a feasible technique in gynecologic surgery with no adverse patient outcomes. PMID: 32612345 [PubMed - in process]
Source: JSLS : Journal of the Society of Laparoendoscopic Surgeons - Category: Surgery Tags: JSLS Source Type: research
Abstract Background: Pectoral nerve block type I (PECS I Block) and type II (PECS II Block) with ropivacaine are relatively new analgesic methods for breast-cancer surgery. We evaluated the safety and efficacy of different concentrations of ropivacaine given in the same volume for the PECS II Block in patients undergoing modified radical mastectomy (MRM). Patients and Methods: One hundred and twenty women undergoing elective MRM who met inclusion criteria were divided randomly into four groups of 30: control group without PECS II Block and R0.2%, R0.3%, and R0.4% groups, who received general anesthesia plus t...
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Tags: Clin Interv Aging Source Type: research
We report four cases of effective analgesia for intractable secondary headache resistant to medical management with high thoracic ESP blocks. In each case, the ESP block provided instant pain relief. We suggest that the findings of this case series indicate that the ESP block may be a useful intervention in patients with severe secondary headache or posterior cervical pain where conventional therapies have limited success, though more studies are necessary. PMID: 32606918 [PubMed]
Source: Local and Regional Anesthesia - Category: Anesthesiology Tags: Local Reg Anesth Source Type: research
Authors: Shrestha N, Karki B, Koirala M, Acharya S, Shrestha PS, Acharya SP PMID: 32606917 [PubMed]
Source: Local and Regional Anesthesia - Category: Anesthesiology Tags: Local Reg Anesth Source Type: research
CONCLUSIONS: Anesthesiologists claim to have knowledge on dysthanasia and orthothanasia, but prefer, in the face of a terminally ill patient, to practice orthothanasia, although dysthanasia is usual, and results in frustration and indignation. The medical school curriculum is unsatisfactory in addressing death-related issues. PMID: 32605825 [PubMed - as supplied by publisher]
Source: Revista Brasileira de Anestesiologia - Category: Anesthesiology Tags: Rev Bras Anestesiol Source Type: research
Authors: Cho HS, Kim S, Kim CS, Kim YJ, Lee JH, Leem JG Abstract Background: General anesthesia (GA) has been considered the anesthetic technique which most frequent leads to phantom limb pain (PLP) after a limb amputation. However, these prior reports were limited by small sample sizes. The aims of this study were to evaluate the incidence of PLP according to the various anesthetic techniques used for limb amputation and also to compare the occurrence of PLP according to amputation etiology using the Korean Health Insurance Review and Assessment Service for large-scale demographic information. Methods: The cla...
Source: Korean Journal of Pain - Category: Anesthesiology Tags: Korean J Pain Source Type: research
Publication date: Available online 1 July 2020Source: Anaesthesia Critical Care &Pain MedicineAuthor(s): Khaled Abdallah, Fadi Hamed, Nadeem Rahman, Shameen Salam, Jihad Mallat
Source: Anaesthesia, Critical Care and Pain Medicine - Category: Anesthesiology Source Type: research
Publication date: Available online 1 July 2020Source: Anaesthesia Critical Care &Pain MedicineAuthor(s): Qian-Bo Chen, Huai-Yu Yang, Shaochun Xu, Zhi-Jie Lu, Liang-Hao Hu
Source: Anaesthesia, Critical Care and Pain Medicine - Category: Anesthesiology Source Type: research
Authors: Garra R, Riso C PMID: 32605357 [PubMed - in process]
Source: Minerva Anestesiologica - Category: Anesthesiology Tags: Minerva Anestesiol Source Type: research
Conclusion: Pentobarbital-loaded decafluorobutane-core Definity-based nanodroplets are a potential agent for ultrasound-triggered and targeted neuromodulation.
Source: Theranostics - Category: Molecular Biology Authors: Tags: Research Paper Source Type: research
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