Glucocorticoid induces human beta cell dysfunction by involving riborepressor GAS5 LincRNA

ConclusionsThe direct adverse effect of glucocorticoid in human beta cell function is mediated via important beta cell proteins and components of the GC signaling pathway in an intricate interplay with GAS5 lincRNA, a potentially novel therapeutic target to counter GC-mediated beta cell dysfunction.
Source: Molecular Metabolism - Category: Endocrinology Source Type: research