Hesperozygis ringens (Benth.) Epling: a study involving extraction, chemical profiling, antioxidant and biological activity.

This study aimed to determine the chemical markers of H. ringens extracts obtained via ultrasound-assisted (UAE-EtOH) and supercritical fluid (SFE-CO2) extractions. UAE-EtOH and SFE-CO2 extracts were characterised by UPLC-MS and GC-MS, respectively. Both products had their antioxidant activity, cytotoxicity and genotoxicity evaluated. Twelve compounds were found in the UAE-EtOH extract, including phenolic acids and flavonoids; the SFE-CO2 extract contained terpenes and phytosterols. The UAE-EtOH extract showed a greater antioxidant activity. Neither extract presented cytotoxicity or genotoxicity against human mononuclear blood cells.
PMID: 31920093 [PubMed - as supplied by publisher]

Source: Natural Product Research - January 9, 2020 Category: Biochemistry Authors: Dolwitsch CB, Pires FB, Frescura LM, Prá VD, Rieffel RC, Sagrillo MR, de Carvalho CA, Mazutti M, Pizzutti IR, da Rosa MB Tags: Nat Prod Res Source Type: research