Silencers, Enhancers, and the Multifunctional Regulatory Genome.
Silencers, Enhancers, and the Multifunctional Regulatory Genome.
Trends Genet. 2020 Jan 07;:
Authors: Halfon MS
Abstract
Negative regulation of gene expression by transcriptional silencers has been difficult to study due to limited defined examples. A new study by Gisselbrecht et al. has dramatically increased the number of identified silencers and reveals that they are bifunctional regulatory sequences that also act as gene expression-promoting enhancers.
PMID: 31918861 [PubMed - as supplied by publisher]
Source: Trends in Genetics : TIG - Category: Genetics & Stem Cells Authors: Halfon MS Tags: Trends Genet Source Type: research