Dexmedetomidine reduces the inflammation and apoptosis of doxorubicin-induced myocardial cells.

In conclusion, this study indicated that DEX could reduce the inflammation and apoptosis of DOX-induced myocardial cells through activating the AMPK-GSK3β signaling pathway. Because of the above effects of DEX, it may be beneficial for surgical patients with heart problems. PMID: 31917290 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31917290?dopt=Abstract

Source: Experimental and Molecular Pathology - January 5, 2020 Category: Pathology Authors: He Y, Yang Z, Li J, Li E Tags: Exp Mol Pathol Source Type: research