Rifampin-moxifloxacin-metronidazole combination therapy for severe Hurley Stage 1 Hidradenitis Suppurativa: prospective short-term trial and one-year follow-up in 28 consecutive patients

Severe Hurley stage 1 Hidradenitis suppurativa (HS1) is a difficult to treat form of the disease.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Authors: Source Type: research

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Publication date: Available online 14 February 2020Source: Actas Dermo-Sifiliográficas (English Edition)Author(s): T. Gracia Cazaña, L.V. Berdel Díaz, J.I. Martín Sánchez, I. Querol Nasarre, Y. GilaberteAbstractTreatment options for hidradenitis suppurativa include light-based therapy. This systematic review aimed to update our understanding of the efficacy, effectiveness and safety of these treatments for hidradenitis suppurativa by evaluating the literature published since the 2015 Cochrane review on this topic. We conducted an electronic search of the following databases: MEDLINE, EMBA...
Source: Actas Dermo-Sifiliograficas - Category: Dermatology Source Type: research
Neutrophilic Dermatoses should be considered in the differential diagnosis, if a patient with abrupt onset of painful erythematous plaques/nodules and elevated erythrocyte sedimentation rate is not responding to antibiotics. AbstractNeutrophilic Dermatoses should be considered in the differential diagnosis, if a patient with abrupt onset of painful erythematous plaques/nodules and elevated erythrocyte sedimentation rate is not responding to antibiotics.
Source: Clinical Case Reports - Category: General Medicine Authors: Tags: CLINICAL IMAGE Source Type: research
This is the first prospective study showing that ASCA are biomarkers for HS, especially in severe inflammatory forms, but not in PV, supporting the contribution of a gut fungal dysbiosis to HS pathogenesis.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research
AbstractChronic inflammatory skin diseases (CISD) represent a significant burden of skin disease in the United States, and a growing number of studies demonstrate that CISD are associated with multiple comorbidities. However, few studies examined multimorbidity in adults with CISD. We sought to determine whether hospitalized US adults with chronic inflammatory skin disorders have increased multi-morbidity and mortality risk. Data from the 2002 –2012 Nationwide Inpatient Sample were analyzed, including a representative 20% sample of US hospitalizations. Charlson comorbidity index (CCI) and mean estimated 10-year survi...
Source: Archives of Dermatological Research - Category: Dermatology Source Type: research
Squamous cell carcinoma arising in hidradenitis suppurativa (HS) is a rare albeit the most serious complication in HS, with a reported fatality of up to 42.9%. This calls for greater clinical awareness in patients with long ‐standing chronic HS. AbstractSquamous cell carcinoma arising in hidradenitis suppurativa (HS) is a rare albeit the most serious complication in HS, with a reported fatality of up to 42.9%. This calls for greater clinical awareness in patients with long ‐standing chronic HS.
Source: Clinical Case Reports - Category: General Medicine Authors: Tags: CASE REPORT Source Type: research
AbstractA recent study of comorbidities in hospitalized pemphigus patients in the United States has demonstrated a significant association of hidradenitis suppurativa (HS) and pemphigus, but this association has not been firmly established in other populations. A retrospective, cross-sectional study was undertaken to determine the prevalence of HS in patients with pemphigus and compare with control subjects. Regression analysis was performed to obtain ORs, and 95% CIs, to evaluate the prevalence between pemphigus patients and controls matched by age, sex, and ethnicity. Among the patients included in the study, 1985 patien...
Source: Archives of Dermatological Research - Category: Dermatology Source Type: research
Source: Journal of the American Academy of Dermatology - Category: Dermatology Authors: Source Type: research
Contributors : Christos C Zouboulis ; Andr é N da Costa ; Sabine Fimmel ; Konstantin C ZouboulisSeries Type : Expression profiling by arrayOrganism : Homo sapiensMolecular taxonomy and key signaling pathways of apocrine glands of patients with hidradenitis suppurativa were studied by whole transcriptome profiling. Dysregulated genes were detected by comparing lesional and non lesional skin obtained from male and female HS patients using the Agilent array platform.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research
Condition:   Hidradenitis Suppurativa Intervention:   Sponsor:   Stanford University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Complementary and alternative medicine (CAM) use is common among patients with hidradenitis suppurativa (HS), more than half of whom report dissatisfaction with conventional treatment, researchers say.Reuters Health Information
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Dermatology News Source Type: news
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