Interleukin-32 γ suppressed atopic dermatitis through inhibition of miR-205 expression via inactivation of nuclear factor-kappa B

Our results demonstrate that IL-32 γ can suppress the development of atopic dermatitis by prevention of pro-inflammatory cytokine release through inhibition of NF-κB-mediated miR-205 expression. IL-32γ could be useful for treatment of atopic dermatitis.

Source: Journal of Allergy and Clinical Immunology - January 9, 2020 Category: Allergy & Immunology Authors: Yong Sun Lee, Sang-Bae Han, Hyeon Joo Ham, Ju Ho Park, Jong Sung Lee, Dae Yeon Hwang, Young Suk Jung, Do Young Yoon, Jin Tae Hong Source Type: research