Intra-cardiac aspergilloma in a normally structured heart: A case report
Publication date: Available online 9 January 2020Source: Journal of Cardiology CasesAuthor(s): Mahmoud Tabandeh, Eshan Bahramali, Zahra Savand Roomi, Soheila Salari, Mohammadreza Radpey, Nadereh ShamsolvaezinAbstractFungal endocarditis is a relatively rare condition which mostly complicates those with intra-cardiac devices and those whose immune system is compromised.Here we present a 63-year-old diabetic man with two-weeks history of weakness and fatigue plus low-grade fever. Transesophageal echocardiography showed a mobile mass attached to the left coronary cusp of the aortic valve which protruded into the left ventricular (LV) outflow tract. Cardiac magnetic resonance further confirmed the presence of a large broad base 18 × 20 × 18 mm mass without gadolinium enhancement suggestive for fungal infection. Voriconazole was administered on the same day after which distal embolization of the mass to distal abdominal aorta ensued shortly. Echocardiography documented the disappearance of the mass from LV outflow tract. Vascular surgeon removed the mass from abdominal aorta immediately and pathology revealed the aspergilloma which was later confirmed by culture. After embolization the patient had become unstable and signs of septic shock occurred which ultimately led to his death in 72 h.Presence of Aspergillus infection in apparently normal cardiac chambers without presence of any intra-cardiac device is extremely rare and the...
ConclusionOur analysis provided strong evidence to indicate a causal relationship between WC and increased risk of CHD.
Publication date: Available online 27 February 2020Source: The American Journal of SurgeryAuthor(s): Lawrence A. Lavery, Kathryn E. Davis, Javier La Fontaine, J. David Farrar, Kavita Bhavan, Orhan K. Oz, Peter A. Crisologo
The objective of this study was to examine the effect of metabolic syndrome on 30-day postoperative complications following corrective surgery for the adult spinal deformity (ASD). Summary of Background Data: Metabolic syndrome has been shown to increase the risk of cardiovascular morbidity and mortality. Few studies have examined the effect of metabolic syndrome on patients with ASD undergoing surgery. Materials and Methods: We performed a retrospective cohort study of patients who underwent spinal fusion for ASD. Patients were divided into 2 groups based on the presence or absence of metabolic syndrome, which was d...
Publication date: Available online 26 February 2020Source: Journal of Advanced ResearchAuthor(s): Heng Zhang, Yaqian Huang, Selena Chen, Chaoshu Tang, Guang Wang, Junbao Du, Hongfang Jin
Conditions: Diabetes Mellitus; Cardiovascular Diseases Interventions: Drug: Renin-angiotensin-aldosterone system inhibitors; Drug: Beta blocker; Drug: SGLT2 Inhibitor - Sodium Glucose Cotransporter Subtype 2 Inhibitor Product Sponsors: National Heart Centre Singapore; Singapore General Hospital; Mackay Memorial Hospital; National Taiwan University Hospital; Peking University People's Hospital; Medanta, The Medicity, India; Public Health&...
Conditions: Diabetes Mellitus, Type 2; Diabetes; Diabetes type2; Type2 Diabetes; Type 2 Diabetes; Type II Diabetes; Hypertension; High Blood Pressure Interventions: Other: DASH4D diet; Other: comparison diet; Other: higher sodium; Other: lower sodium Sponsors: Johns Hopkins University; Beth Israel Deaconess Medical Center Not yet recruiting
Condition: Pre-Diabetic Interventions: Drug: Calcitriol capsules; Drug: Oral Placebo Sponsor: Mayo Clinic Not yet recruiting
Condition: Type2 Diabetes Mellitus Interventions: Drug: Glucophage 500Mg Tablet; Drug: Acarbose Tablets; Drug: Sitagliptin tablet; Drug: Dapagliflozin Tablet; Drug: Pioglitazone Tablets; Drug: Glimepiride Tablets Sponsors: Peking Union Medical College Hospital; Chinese Academy of Sciences Not yet recruiting
Condition: Diabetes Mellitus, Type 2 Intervention: Drug: Semaglutide Sponsor: Novo Nordisk A/S Not yet recruiting
Condition: Neuropathy, Diabetic Interventions: Behavioral: Progressive muscle relaxation; Behavioral: Mindfulness meditation; Other: Attention matched control Sponsor: Hacettepe University Completed