Cancers, Vol. 12, Pages 179: Evaluation of Calcium Electroporation for the Treatment of Cutaneous Metastases: A Double Blinded Randomised Controlled Phase II Trial

The objective response rates were 33% (6/18) for Ca-EP and 53% (8/15) for bleomycin-based ECT, with 22% (4/18) and 40% (6/15) complete response rates, respectively. The CR was confirmed histologically in both arms. Serious adverse events were not registered. Ulceration and hyperpigmentation, both CTCA criteria grade I side effects, were observed more frequently after bleomycin-based ECT than for Ca-EP. Ca-EP was non-inferior to ECT, therefore, it should be considered as a feasible, effective and safe treatment option.

Source: Cancers - January 9, 2020 Category: Cancer & Oncology Authors: Ágoston Balt ás Ócsai R átkai L ázár Korom Varga N émeth D ósa-Rácz Viharosné Gehl Ol áh Kem ény Kis Tags: Article Source Type: research