New possible strategy for treating chronic pain due to burns may help sufferers including veterans

(The Physiological Society) New research shows how second-degree burns cause hard-to-treat chronic pain, and this understanding may be key to treating these complications, common in war veterans This research, published in Physiological Reports, suggests that burns cause changes to neurons in multiple parts of the spinal cord, even far from the injury site, which can contribute to chronic pain and other long-term complications.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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What does physical pain have to do with depression, and vice versa? On today’s Psych Central Podcast, our guest, Dr. Jack Stern, a board-certified neurosurgeon specializing in spinal surgery, explains the psychology of pain and how the two are inextricably linked. Dr. Stern describes how pain can lead to depression and how depression can intensify physical pain. We also find out why opioids don’t work for chronic pain, and how past pain affects current pain. Join us for an in-depth discussion on physical pain and mental health. SUBSCRIBE &REVIEW Guest information for ‘Dr. Jack Stern- Chronic Pain&r...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Chronic Pain Depression Disorders General Interview Mental Health and Wellness Podcast Psychology The Psych Central Show Source Type: blogs
The future of healthcare is shaping up in front of our very eyes with advances in digital technologies, such as artificial intelligence, VR/AR, 3D-printing, robotics or nanotechnology. We have to familiarize with the latest developments in order to be able to control technology and not the other way around. The future of healthcare lies in working hand-in-hand with technology and healthcare workers have to embrace emerging technologies in order to stay relevant in the coming years. Be bold, curious and informed! Are you afraid that robots will take over the jobs of nurses, doctors and other healthcare professionals? Are y...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Future of Medicine 3d printing AI artificial intelligence augmented reality genetics Health Healthcare nanotechnology Personalized medicine pharma pharmacology robotics virtual reality wearables GC1 Source Type: blogs
This study is the first report of evidence demonstrating that a second‐degree bu rn injury significantly affects motor neuron structure within the spinal cord. Furthermore, our results support the opportunity to study dendritic spine dysgenesis as a novel avenue to clarify the complexities of neurological disease following traumatic injury.
Source: Physiological Reports - Category: Physiology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Publication date: Available online 18 September 2019Source: Arthroscopy TechniquesAuthor(s): Justin Hallock, Larry D. FieldAbstractThe formation of heterotopic ossification around the shoulder is a rare but potentially debilitating condition. It is found most commonly around the hip and is usually associated with an inciting event such as trauma, burn, previous surgery, or traumatic brain/spinal cord injury. The formation of shoulder heterotopic ossification following arthroscopic surgery is very uncommon, with few data pertaining to it in the current literature. Formation of heterotopic ossification in the shoulder after ...
Source: Arthroscopy Techniques - Category: Surgery Source Type: research
We examined the expression of TRPV1 in peripheral tissue and DRG neurons of CPIP model rats and we studied whether CPIP model could induce peripheral sensitization of TRPV1 channel and enhance DRG neuron excitability. Then we examined the therapeutic effects of locally applied TRPV1 specific antagonist AMG9810 on pain responses of CPIP model rats. Lastly, we explored the effects of AMG9810 on DRG neuron hyperexcitability and spinal glial activation induced by CPIP. Our results demonstrate that TRPV1 plays an important role in mediating the behavioral hypersensitivity of CPIP model rats via promoting peripheral nociceptor a...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
It is a great privilege to have developed this issue of the Physical Medicine and Rehabilitation Clinics of North America dedicated to upholding Abraham Lincoln ’s declaration during his second Inaugural Address, “To care for him who shall have borne the battle and for his widow, and his orphan,” by focusing on the specialized rehabilitation needs of Polytrauma Rehabilitation in the Military and Veteran Populations. Polytrauma, defined as “two or mo re injuries, one of which may be life threatening, sustained in the same incident that affect multiple body parts or organ systems and result in physica...
Source: Physical Medicine and Rehabilitation Clinics of North America - Category: Rehabilitation Authors: Source Type: research
Publication date: May 2017 Source:PM&R, Volume 9, Issue 5, Supplement Author(s): Adam S. Tenforde, Jaye E. Hefner, Jodi E. Kodish-Wachs, Mary A. Iaccarino, Sabrina Paganoni Telehealth refers to health care interactions that leverage telecommunication devices to provide medical care outside the traditional face-to-face, in-person medical encounter. Technology advances and research have expanded use of telehealth in health care delivery. Physical medicine and rehabilitation providers may use telehealth to deliver care to populations with neurologic and musculoskeletal conditions, commonly treated in both acute care and ...
Source: PMandR - Category: Rehabilitation Source Type: research
This study is the first CAR T-cell trial to infuse patients with an even mixture of two types of T cells (helper and killer cells, which work together to kill cancer). With the assurance that each patient gets the same mixture of cells, the researchers were able to come to conclusions about the effects of administering different doses of cells. In 27 of 29 participants whose responses were evaluated a few weeks after the infusion, a high-sensitivity test could detect no trace of their cancer in their bone marrow. The CAR T cells eliminated cancers anywhere in the body they appeared. Of the two participants who did n...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
ABSTRACT: Extremity trauma, spinal cord injuries, head injuries, and burn injuries place patients at high risk of pathologic extraskeletal bone formation. This heterotopic bone causes severe pain, deformities, and joint contractures. The immune system has been increasingly implicated in this debilitating condition. This review summarizes the various roles immune cells and inflammation play in the formation of ectopic bone and highlights potential areas of future investigation and treatment. Cell types in both the innate and adaptive immune system such as neutrophils, macrophages, mast cells, B cells, and T cells have all b...
Source: Journal of Trauma and Acute Care Surgery - Category: Surgery Tags: Review Articles Source Type: research
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