Utilization Patterns of Amantadine in Parkinson ’s Disease Patients Enrolled in the French COPARK Study

ConclusionsIn this cohort, amantadine was used in 10% of patients. Its use increased during follow-up, despite the fact that one-third of patients who received amantadine at baseline stopped taking it. Amantadine prescription was mainly correlated with the presence of dyskinesia.
Source: Drugs and Aging - Category: Geriatrics Source Type: research

Related Links:

What exactly is psychosis? What happens in the brain of a person with schizophrenia who is hallucinating? Schizophrenic Rachel Star Withers shares her personal hallucinations and delusions and Dr. Joseph Goldberg, who specializes in researching what goes on in the brain when someone is experiencing psychosis, joins to break down how the brain functions during psychotic episodes. Host Rachel Star Withers, a diagnosed schizophrenic, and co-host Gabe Howard delve into these intense subjects in this episode of Inside Schizophrenia.  Highlights from “Psychosis in Schizophrenia” Episode [02:13]  Rachel, do...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Brain and Behavior Disorders General Inside Schizophrenia Mental Health and Wellness Active psychosis Delusions Delusions Hallucinations Living with Schizoprenia Mental Disorder Mental Illness Psychology psychotic Psychotic Break Source Type: blogs
 Rachel Star Withers is a speaker, YouTuber, and lives with schizophrenia. She is also a professional stunt woman and tends to describe herself as a “schizo stunt girl.”     In this episode, Rachel tells us a little of her history with the disease and details how she first started in mental illness activism.  Originally meant to just help other people with schizophrenia know that they were not alone, her YouTube channel, RachelStarLive, has become the longest existing chronicle of a personal experience with schizophrenia.  Listen Now! SUBSCRIBE &REVIEW   Guest information for &...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Peer Support Podcast Schizophrenia The Psych Central Show Source Type: blogs
Conclusions The treatment used for PD, particularly DA, is associated with the development of ICDs and related behaviors. Susceptibility to these disorders depends on the associated risk factors. ICDs can have serious personal, family, psychosocial, financial, and medical consequences. However, in contrast, artistic activities have been described in patients with PD while undergoing treatment with DA. These patients are compulsive but report a positive influence on quality of life. These findings highlight the need for a very critical approach at the moment of Dopaminergic Replacement therapy choice. Author Contributio...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Authors: Crippa JAS, Hallak JEC, Zuardi AW, Guimarães FS, Tumas V, Dos Santos RG Abstract Parkinson's disease (PD) is a chronic neurodegenerative disorder characterized by motor symptoms such as bradykinesia, rest tremor, postural disturbances, and rigidity. PD is also characterized by non-motor symptoms such as sleep disturbances, cognitive deficits, and psychiatric disorders such as psychosis, depression, and anxiety. The pharmacological treatment for these symptoms is limited in efficacy and induce significant adverse reactions, highlighting the need for better treatment options. Cannabidiol (CBD) is a ph...
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research
AbstractParkinson ’s disease (PD) is a chronic neurodegenerative disorder characterized by motor symptoms such as bradykinesia, rest tremor, postural disturbances, and rigidity. PD is also characterized by non-motor symptoms such as sleep disturbances, cognitive deficits, and psychiatric disorders such as psychosis , depression, and anxiety. The pharmacological treatment for these symptoms is limited in efficacy and induce significant adverse reactions, highlighting the need for better treatment options. Cannabidiol (CBD) is a phytocannabinoid devoid of the euphoriant and cognitive effects of tetrahydrocannabi nol, a...
Source: European Archives of Psychiatry and Clinical Neuroscience - Category: Neuroscience Source Type: research
AbstractThe gold standard of treatment in Parkinson ’s disease (PD) is levodopa/carbidopa whose long-term use induces motor and non-motor fluctuations and dyskinesias. Continuous infusion of intrajejunal levodopa/carbidopa intestinal gel (Duodopa®) reduces motor and non-motor symptoms and dyskinesias, and improves the quality of life of patients. The aim of this open observational prospective study was to evaluate the impact of Duodopa® on conditions of PD patients and caregivers, and their quality of life. We enrolled 12 patients with advanced PD and their caregivers. The PD patients were assessed at baselin...
Source: Journal of Neurology - Category: Neurology Source Type: research
We describe their treatment and review the current literature on the use of ECT among patients with PD. CASE SERIES All six patients in our retrospective chart review received bitemporal modified brief pulse ECT. Prior to ECT, the patients underwent pre-ECT evaluation, which involved hemogram analysis, renal and liver function tests, fasting blood glucose analysis, chest X-ray (posteroanterior view), and serum electrolyte analysis, all of which were within the normal range for all six patients, and none of the patients showed evidence of raised intracranial pressure on fundoscopy examination. All patients provided written ...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Case Review Current Issue Depression Devices ECT Mental Disorders Mood Disorders Movement Disorders Neurology Parkinson's disease Psychiatry Technology Electroconvulsive therapy parkinson’s disease Source Type: research
This study aims to address the vascular depression hypothesis in Parkinson's disease (PD) from a large cohort of Chinese population. MethodsA cross‐sectional analysis of 1784 Chinese patients with PD was conducted. Patients were divided into absence of depression (score ≤ 20) and presence of depression (score> 20) based on the assessment of Hamilton Depression Rating Scale (HDRS). Other clinical assessments included Unified PD Rating Scale (UPDRS), Hamilton Anxiety Rating Scale (HARS), Frontal assessment battery (FAB) and Montreal Cognitive Assessment (MoCA). ResultsPatients with depression showed higher proportion...
Source: European Journal of Neurology - Category: Neurology Authors: Tags: Original Article Source Type: research
Conclusions: In patients with TD, deutetrabenazine was well tolerated and significantly reduced abnormal movements. Classification of evidence: This study provides Class I evidence that in patients with TD, deutetrabenazine reduces AIMS scores.
Source: Neurology - Category: Neurology Authors: Tags: Clinical trials Randomized controlled (CONSORT agreement), Class I ARTICLE Source Type: research
Conclusions:Our findings suggest that ICD patients have more insomnia, BSD and hallucinations than non-ICD PD patients. The ICD prevalence was lower than has been reported, suggesting that it is grossly underreported and underscreened in our large PD population. This information allows us to better identify risk factors and screening methods in future ICD patients.Disclosure: Dr. Rossi has nothing to disclose. Dr. Stebbins has received personal compensation for activities with Acadia, Pharmaceuticals, Adamas Pharmaceuticals, Inc., Ceregene, Inc., CHDI Management, Inc., Ingenix Pharmaceutical Services (i3 Research), Neurocr...
Source: Neurology - Category: Neurology Authors: Tags: Parkinson ' s Disease: Non-Motor Manifestations Source Type: research
More News: Amantadine | Anxiety | Brain | Carbidopa/Levodopa | Deep Brain Stimulation | Depression | Dyskinesia | France Health | Geriatrics | Men | Neurology | Parkinson's Disease | Study | Symmetrel