Importance of avoiding late cancer-directed therapy in terminally ill cancer patients

SummaryIt is undeniably a  great challenge to adequately weigh the benefits and harms of tumor-specific therapy near the end of life and to find the right time for changing the objective of therapy to palliative care alone. In a curative situation, the “survival” benefit of the treatment outweighs its potential harm du e to side effects. However, things are different when the possibility of cure is ruled out. Important prerequisites to avoid overly zealous care are adequate communication about the therapeutic options and consensus between the doctor and the patient with regard to the (realistic) therapeutic goal, a realistic estimated prognosis and early integration of palliative care.
Source: Memo - Magazine of European Medical Oncology - Category: Cancer & Oncology Source Type: research

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Curative treatments for metastatic prostate, renal, and urothelial cancer should continue as usual amid the pandemic, but palliative and (neo)adjuvant treatments should be reconsidered, experts say.Medscape Medical News
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In conclusion, survival of GBC remains poor. Radical surgery and palliative chemotherapy appear to improve prognosis but remain under-utilized.
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
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Funding Opportunity RFA-CA-20-030 from the NIH Guide for Grants and Contracts. Through this Funding Opportunity Announcement (FOA), the NCI invites applications to support research in new and innovative cohort studies that identify clinical, lifestyle, genomic, and other factors that affect health outcomes (e.g., morbidity, mortality, quality of life, physical, social, and psychological outcomes) in cancer survivors. This RFA supports research that requires the creation of a new prospective cohort study of cancer survivors that addresses a gap in knowledge pertaining to the health of cancer survivors. Proposals must ident...
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding
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Source: Endoscopy - Category: Gastroenterology Authors: Tags: Guideline Source Type: research
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Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research
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Source: Current Treatment Options in Gastroenterology - Category: Gastroenterology Source Type: research
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