A new coronavirus causing respiratory disease in China

A new coronavirus appears to be causing a pneumonia-like illness in China. It is certainly a zoonotic infection – jumping from non-human animals to humans – as exemplified by previous outbreaks of SARS and MERS coronaviruses. The government in Wuhan, China confirmed on 31 December that dozens of cases of pneumonia of unknown cause were […]
Source: virology blog - Category: Virology Authors: Tags: Basic virology Information coronavirus emerging virus MERS pneumonia respiratory disease SARS viral viruses Wuhan outbreak zoonosis Source Type: blogs

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Source: BMJ Comments - Category: General Medicine Source Type: forums
Source: BMJ Comments - Category: General Medicine Source Type: forums
Source: BMJ Comments - Category: General Medicine Source Type: forums
ConclusionsThe CAUTI incidence is reduced through QCC, providing a useful reference for the prevention of CAUTI and the development of medical quality improvement activities.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
AbstractWarfarin is a narrow therapeutic index anticoagulant drug, and several generic formulations have been approved worldwide. However, there has been no report evaluating the bioequivalence of warfarin sodium according to US Food and Drug Administration draft guidance. We designed a 2 ‐sequence and 4‐period crossover study to compare the pharmacokinetic profile and assess bioequivalence between the test warfarin sodium tablet and reference product Coumadin (2.5 mg) in 56 healthy Chinese subjects under fasting and fed conditions. The plasma concentration of warfarin was analy zed by a validated liquid chromatog...
Source: Clinical Pharmacology in Drug Development - Category: Drugs & Pharmacology Authors: Tags: Original Manuscript Source Type: research
Abstract Intergenic region of begomovirus genome is vital to virus replication and viral gene transcription in plants. Previous studies have reported that Tomato yellow leaf curl China virus (TYLCCNV), a begomovirus, is able to accumulate and transcribe in its whitefly vector. However, the viral and host components that participate in begomovirus transcription in whiteflies are hitherto unknown. Using a yeast one-hybrid system, we identified>50 whitefly proteins that interacted with TYLCCNV intergenic region. Dual luciferase analysis revealed that one of the identified proteins, the hairy and enhancer of split ...
Source: Virology - Category: Virology Authors: Tags: Virology Source Type: research
Publication date: Available online 4 February 2020Source: Microbes and InfectionAuthor(s): Jieliang ChenAbstractA zoonotic coronavirus, labeled as 2019-nCoV by The World Health Organization (WHO), has been identified as the causative agent of the viral pneumonia outbreak in Wuhan, China, at the end of 2019. Although 2019-nCoV can cause a severe respiratory illness like SARS and MERS, evidence from clinics suggested that 2019-nCoV is generally less pathogenic than SARS-CoV, and much less than MERS-CoV. The transmissibility of 2019-nCoV is still debated and needs to be further assessed. To avoid the 2019-nCoV outbreak turnin...
Source: Microbes and Infection - Category: Infectious Diseases Source Type: research
This reporter was once served slices of sashimi still attached to the carcass of a gasping fish.) Eating wild animals is also considered a luxury because of their rarity and cost, much like game is in the West. Some practitioners of Traditional Chinese Medicine also believe that eating exotic creatures can cure certain ailments and boost “male potency.” “This is just part of Chinese culture,” says Yanzhong Huang, a public heath expert at the Council for Foreign Relations. “They love to eat anything alive.” Wild animals are, of course, especially problematic because their murky provenienc...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized China Infectious Disease onetime overnight Source Type: news
BOSTON (CBS/CNN) – A new Chinese coronavirus, a cousin of the SARS virus, has infected more than 200 people since the outbreak began in Wuhan, China, in December. Boston’s Logan Airport is not currently screening passengers for the illness, a spokesman for Customs and Border Protection told WBZ-TV. That’s because there are no direct flights to Boston from that region. Additional health screening for coronavirus is in place at JFK Airport in New York, San Francisco International Airport and Los Angeles International Airport. The agency said the CDC has determined that coronavirus presents a low risk to the...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Syndicated CBSN Boston Coronavirus Logan Airport Source Type: news
Publication date: 2019Source: Advances in Virus Research, Volume 105Author(s): M. Alejandra Tortorici, David VeeslerAbstractCoronaviruses (CoVs) have caused outbreaks of deadly pneumonia in humans since the beginning of the 21st century. The severe acute respiratory syndrome coronavirus (SARS-CoV) emerged in 2002 and was responsible for an epidemic that spread to five continents with a fatality rate of 10% before being contained in 2003 (with additional cases reported in 2004). The Middle-East respiratory syndrome coronavirus (MERS-CoV) emerged in the Arabian Peninsula in 2012 and has caused recurrent outbreaks in humans w...
Source: Advances in Virus Research - Category: Virology Source Type: research
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