Does longer sevoflurane preconditioning contribute to better neuroprotective effects?

(Neural Regeneration Research) Sevoflurane belongs to volatile anesthetics, and preconditioning with sevoflurane has been shown to exert protective effects against ischemic injury in the brain. But the mechanism is unclear.
Source: EurekAlert! - Medicine and Health - Category: Global & Universal Source Type: news

Related Links:

Publication date: Available online 4 July 2020Source: Best Practice &Research Clinical AnaesthesiologyAuthor(s): Kyle Gress, Karina Charipova, Daniel An, Jamal Hasoon, Alan D. Kaye, Antonella Paladini, Giustino Varrassi, Omar Viswanath, Alaa Abd-Elsayed, Ivan Urits
Source: Best Practice and Research Clinical Anaesthesiology - Category: Anesthesiology Source Type: research
Publication date: Available online 3 July 2020Source: Best Practice &Research Clinical AnaesthesiologyAuthor(s): Eleni Moka, Antonella Paladini, Martina Rekatsina, Ivan Urits, Omar Viswanath, Alan D. Kaye, Cheng Teng Yeam, Giustino Varrassi
Source: Best Practice and Research Clinical Anaesthesiology - Category: Anesthesiology Source Type: research
Publication date: Available online 3 July 2020Source: Best Practice &Research Clinical AnaesthesiologyAuthor(s): Ivan Urits, Cynthia Pham, Daniel Swanson, Kevin Berardino, Prudhvi Bandi, Ariunzaya Amgalan, Rachel J. Kaye, Jai Won Jung, Alan D. Kaye, Antonella Paladini, Giustino Varrassi, Adam M. Kaye, Laxmaiah Manchikanti, Omar Viswanath
Source: Best Practice and Research Clinical Anaesthesiology - Category: Anesthesiology Source Type: research
Publication date: Available online 3 July 2020Source: Best Practice &Research Clinical AnaesthesiologyAuthor(s): Ivan Urits, Nathan Li, Ehab Bahrun, Hayk Hakobyan, Lekha Anantuni, Daniel An, Amon A. Berger, Alan D. Kaye, Antonella Paladini, Giustino Varrassi, Kevin E. Vorenkamp, Omar Viswanath
Source: Best Practice and Research Clinical Anaesthesiology - Category: Anesthesiology Source Type: research
Abstract A single sub-anesthetic intravascular dose of the use-dependent NMDAR antagonist, ketamine, improves mood in patients with treatment resistant depression within hours that can last for days, creating an entirely new treatment strategy for the most seriously ill patients. However, the psychomimetic effects and abuse potential of ketamine require that new therapies be developed that maintain the rapid antidepressant effects of ketamine without the unwanted side effects. This necessitates a detailed understanding of what cellular and synaptic mechanisms are immediately activated once ketamine reaches the bra...
Source: Advances in Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Adv Pharmacol Source Type: research
Abstract A serious lack of effective pharmacotherapeutic interventions for posttraumatic stress disorder (PTSD) raises the urgent need for the development of novel treatments. Ketamine-a noncompetitive glutamate N-methyl-d-aspartate (NMDA) receptor antagonist in use for decades as an anesthetic and analgesic agent-has more recently been demonstrated to have rapid-onset antidepressant effects in patients with treatment-resistant depression (TRD). In the present review of ketamine as an emerging novel pharmacotherapeutic intervention for chronic PTSD, we discuss findings from the first proof-of-concept, randomized c...
Source: Advances in Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Adv Pharmacol Source Type: research
Abstract Major depressive disorder (MDD) is a debilitating illness with significant morbidity and mortality, leading to attempted and completed suicides. It affects interpersonal relationships and also contributes to decreased productivity, causing financial burden to individuals and society. Patients often fail to respond to various antidepressant medication trials resulting in treatment-resistant depression (TRD). Current antidepressant medications work by modulating the monoaminergic systems and takes several weeks to establish a clinical response. Ketamine has been used extensively as an anesthetic agent since...
Source: Advances in Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Adv Pharmacol Source Type: research
Conclusion: RFA-EMT, a new technique, is safe and effective for women with HMB or AUB for which medical therapy has failed. PMID: 32619371 [PubMed - as supplied by publisher]
Source: International Journal of Hyperthermia - Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research
Publication date: Available online 4 July 2020Source: Orthopaedics &Traumatology: Surgery &ResearchAuthor(s): Sang Ki Lee, Sung Gul Kim, Won Sik Choy
Source: Orthopaedics and Traumatology: Surgery and Research - Category: Orthopaedics Source Type: research
Publication date: Available online 3 July 2020Source: Anaesthesia Critical Care &Pain MedicineAuthor(s): Laurent Zieleskiewicz, Gary Duclos, Ophélie Dransart-Rayé, Nicolas Nowobilski, Belaid Bouhemad
Source: Anaesthesia, Critical Care and Pain Medicine - Category: Anesthesiology Source Type: research
More News: Anesthesia | Anesthesiology | Brain | Health | International Medicine & Public Health | Neurology | Sevoflurane | Ultane