Characterization of Immune Dysfunction and Identification of Prognostic Immune-related Risk Factors in Acute Myeloid Leukemia.

CONCLUSIONS: T cell senescence and exhaustion, together with impaired NK and γδ T cell function, are dominant aspects involved in immune dysfunction in AML. Non-invasive immune testing of blood samples could be applied to predict therapeutic reactivity, high risk for relapse and unfavorable prognosis. PMID: 31911547 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31911547?dopt=Abstract

Source: Clinical Cancer Research - January 6, 2020 Category: Cancer & Oncology Authors: Tang L, Wu J, Li CG, Jiang HW, Xu M, Du M, Yin Z, Mei H, Hu Y Tags: Clin Cancer Res Source Type: research