Abnormal reward valuation and event-related connectivity in unmedicated major depressive disorder.
CONCLUSIONS: Our findings support the theory that abnormal neural reward valuation plays a central role in major depressive disorder (MDD). To the extent that emotion reflects valuation, abnormal valuation could explain abnormal emotional experience in MDD, reflect a core pathophysiological process and be a target of treatment.
PMID: 31907081 [PubMed - as supplied by publisher]
Source: Psychological Medicine - Category: Psychiatry Authors: Rupprechter S, Stankevicius A, Huys QJM, Series P, Steele JD Tags: Psychol Med Source Type: research