Intra ‐individual association between C‐reactive protein and insulin administration in postoperative lumbar spinal canal stenosis patients: a retrospective cohort study

AbstractThe association of intra ‐individual variability in insulin requirements with C‐reactive protein (CRP) levels among acute phase patients remains unclear. This retrospective cohort study aimed to evaluate this association. Patients with type 2 diabetes undergoing surgery for lumbar spinal canal stenosis were included in the study. We analyzed 286 records of 49 patients using the linear mixed‐effect model. The model showed CRP levels to be significantly associated with insulin requirements, with an effect size of 0.60 U/day for an elevation of 1 mg/dL. The effect size was increased in patients with higher hemoglob in A1c levels. Our findings imply that CRP levels could be a useful clinical biomarker when blood glucose levels are controlled in acute phase patients.
Source: Journal of Diabetes Investigation - Category: Endocrinology Authors: Tags: SHORT REPORT Source Type: research