FSU study aids fight against HIV, hepatitis B

(Florida State University) A discovery by Florida State University College of Medicine researchers is expected to open the door for new and more potent treatment options for many of the more than 36 million people worldwide infected with the HIV virus and for others chronically ill with hepatitis B.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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We described the frequency of disease overlaps; for example, 34.7% of clients with a syphilis record had a gonorrhea record. We quantified known overlaps, finding 1274 clients had gonorrhea, infectious syphilis, and HIV/AIDS records, and potentially emerging overlaps, finding 59 clients had HIV/AIDS, hepatitis C, and iGAS records. IMPLICATIONS: Our novel person-based integrated surveillance dataset represents a platform for ongoing in-depth assessment of disease overlaps such as the relative timing of disease records. It enables a more client-focused approach, is a step towards improved characterization of syndemics i...
Source: Canadian Journal of Public Health - Category: International Medicine & Public Health Authors: Tags: Can J Public Health Source Type: research
Using a gene sequencing approach, this study examined the gut microbiota profile of patients with hepatitis B virus-induced chronic liver disease compared with healthy controls.Journal of Viral Hepatitis
Source: Medscape Hiv-Aids Headlines - Category: Infectious Diseases Tags: Gastroenterology Journal Article Source Type: news
Currently, a functional cure for hepatitis B virus infection is rare. This review summarizes the efficacy, safety and pharmacology of the many compounds under investigation for the treatment of HBV.Alimentary Pharmacology &Therapeutics
Source: Medscape Hiv-Aids Headlines - Category: Infectious Diseases Tags: Gastroenterology Journal Article Source Type: news
ConclusionsThere is a definite need for a Transition Clinic in the management of adolescents with chronic illness to ensure smooth transfer of care. Introducing such clinics in the existing health framework is feasible using a multidisciplinary approach.
Source: Indian Journal of Pediatrics - Category: Pediatrics Source Type: research
Abstract From December 2006 to December 2016, 1093 human immunodeficiency virus (HIV) individuals
Source: J Korean Med Sci - Category: General Medicine Authors: Tags: J Korean Med Sci Source Type: research
This study assessed which HIV care quality indicators were associated with healthcare resource utilization and costs. Design: Retrospective analysis of Texas Medicaid claims data (01 January 2012 to 31 September 2016). Methods: Included patients had at least two HIV-related medical claims during the identification period (01 July 2012 to 31 August 2014) (index = date of first HIV claim), were 18–62 years at index, and were continuously enrolled in the 6-month pre-index and 1-year post-index periods. Dependent variables included emergency department (ED) visits, inpatient hospitalizations, prescription count...
Source: AIDS - Category: Infectious Diseases Tags: Epidemiology and Social Source Type: research
(Natural News) Did you know that, just prior to the HIV and AIDS epidemic that swept the American homosexual population during the early 1980s, the Centers for Disease Control and Prevention (CDC) had conducted a hepatitis B vaccine experiment that’s believed to have triggered it? Between the years of 1978 and 1981, the CDC specifically...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Difficulties in confirming and discriminating human T-cell lymphotropic virus type 1 (HTLV-1) and HTLV-2 infections by serological Western blot (WB) assays (HTLV Blot 2.4; MP Biomedicals) have been reported in Brazil, mainly in HIV/AIDS patients, with a large number of WB-indeterminate and WB-positive but HTLV-untypeable results. Nonetheless, a line immunoassay (LIA) (INNO-LIA HTLV-I/II; Fujirebio) provided enhanced specificity and sensitivity for confirming HTLV-1/2 infections. To add information concerning the improved ability of the LIA in relation to WB when applied to samples of individuals from different risk groups ...
Source: Journal of Clinical Microbiology - Category: Microbiology Authors: Tags: Immunoassays Source Type: research
Abstract Hepatitis B surface antigen (HBsAg) level plays an important role in conjunction with other markers such as hepatitis B envelope antigen (HBeAg) and hepatitis B virus (HBV) deoxyribonucleic acid levels to predict disease activity in chronic Hepatitis B (CHB). Quantification of HBsAg is useful in differentiating carriers from active hepatitis in HBeAg negative patients, and current guidelines recommend monitoring of pegylated interferon alpha treatment in CHB infection. However, there are only few studies about the role of quantitative HBsAg (qHBsAg) monitoring in HIV-HBV coinfected patients. Studies have ...
Source: AIDS Reviews - Category: Infectious Diseases Authors: Tags: AIDS Rev Source Type: research
Abstract Virus-like particles (VLPs) are a type of subunit vaccine which resembles viruses but do not contain any genetic material so that they are not infectious. VLPs maintain the same antigenic conformation to the original virus, and they could be a better vaccine candidate than live-attenuated and inactivated vaccines. In addition, compared to other subunit vaccines such as soluble protein, VLPs can stimulate both innate and adaptive immune responses effectively and safely against several pathogens by the closer morphology to its native virus. They have already been licensed as vaccines against Hepatitis B vir...
Source: AIDS Reviews - Category: Infectious Diseases Authors: Tags: AIDS Rev Source Type: research
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