Disseminated Blastomycosis Presenting as Obstructive Renal Mass Treated with Fluconazole
A 78-year-old male with hypertension, chronic kidney disease, and urothelial carcinoma excised 3 years prior presented with lower abdominal pain and weight loss. He had been experiencing progressive anorexia, weakness, and a 30-pound weight loss before presentation.
Do you folks have any ideas for my next PIP? I did the back pain one a few years ago and it wasn't too bad. Can I do same one (from AAPMR) again? The other projects don't really pertain to my practice. Any other recommendations?
CONCLUSIONS: The average patient is middle aged (often male) with a history of subacute back pain, sometimes presenting fever and/or neurological damage on diagnosis. Acute phase reactants are frequently raised. Diabetes mellitus, endocarditis and immunosuppressed patients may have the worst chance of a good outcome, therefore these patients should be more carefully managed (always try to obtain an imaging-guided biopsy, correct antibiotic treatment, and a functional and clinical follow-up). PMID: 32446680 [PubMed - as supplied by publisher]
Publication date: May 2020Source: Journal of Comparative Pathology, Volume 177Author(s): L.M.C. Soares, A.H.B. Pereira, C.G. de Campos, L.S. Rocha, T.Á. dos Santos, M.A. Souza, P.C. Jark, C.A. Pescador
HIGH BLOOD PRESSURE may seem harmless but the condition can be a precursor to heart disease so it is important to keep it in check. Nuts have been shown to have a moderating effect on blood pressure and one nut comes out on top.
Publication date: Available online 25 May 2020Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Paul Ryan, Mark Sheehy
Publication date: Available online 24 May 2020Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Mariana Y Puerta, Ricardo Galhardoni, Manoel Jacobsen Teixeira, Jose Tadeu Tesseroli de Siqueira, Silvia Regina Dowgan Tesseroli de Siqueira
This study, for instance, attributes a patient’s waitlist/transplant outcome to the very last dialysis facility the patient was associated with. In epidemiology speak, this means the causal inference authors are trying to draw between for-profit status and good transplant outcomes is subject to time-varying confounding. As an example, if one is seeking an association between testosterone levels and risk of a heart attack, using the last testosterone level available would be a poor way of doing this study because testosterone levels are known to vary over time. The same applies to dialysis facilities. Patie...
Publication date: 5 August 2020Source: Journal of Pharmaceutical and Biomedical Analysis, Volume 187Author(s): Valentina Iacuzzi, Martina Zanchetta, Sara Gagno, Ariana Soledad Poetto, Marco Orleni, Elena Marangon, Michela Guardascione, Luisa Foltran, Bianca Posocco, Giuseppe Toffoli
Conclusions VHL/PBRM1 mutations confirmed 3rd subtype identified and under review but appears to be mis-classified tumors. Shows value of molecular methods rather than new mechanistic insights. Integration with survival outcome—suggests molecular detailing can be prognostic Full integrative analysis in process Preliminary data can be found at http://tcga-data.nci.hih.gov/tcga/ FoxO Transcription Factors in mTORC1- Activated Renal Tumorigenesis: Implications for the RCC Treatment Boyi Gan, MD Anderson Cancer Center FoxO Family Transcription Factors: mammals possess FoxO...