Penn study paves way for new vaccines to protect infants against infections

(University of Pennsylvania School of Medicine) A new Penn Medicine study puts researchers within closer reach of vaccines that can protect infants against infections by overcoming a mother's antibodies, which are known to shut down immune defenses initiated by conventional vaccines. That hurdle largely explains why vaccinations for infectious diseases like influenza and measles not given until six to 12 months of age. Findings from the preclinical study were published online today in Science Translational Medicine.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news

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Mark Sumner at DK has aroundup of news from overwhelmed health care systems around the country. This seems to be getting very little attention from national media, for some reason -- this is a list of local stories, which don't seem to have gotten the attention of editors at CNN or the New York Times.This is definitely bad news in the present, but it's better news in the long run. The Covid-19 variant that's causing this is extremely contagious -- as contagious a measles, apparently. That means you can become infected just by briefly being in the vicinity of an infectious person. One thing that's really unpleasant about th...
Source: Stayin' Alive - Category: American Health Source Type: blogs
Guillain–Barre syndrome (GBS), the most frequent cause of acute paralytic neuropathy, is an inflammatory polyneuropathy that is autoimmune in nature. Many infectious agents such as Campylobacter jejuni (the most commonly identified bacteria associated with GBS), cytomegalovirus, Epstein–Barr virus, measles virus, influenza A virus, and Mycoplasma pneumonia, as well as enterovirus D68 and Zika virus and noninfectious agents such as vaccines and surgeries have been reported to trigger GBS. Three main variants of GBS include the classic acute inflammatory demyelinating polyneuropathy (AIDP), which is the most comm...
Source: Reviews in Medical Microbiology - Category: Microbiology Tags: FOCUS ON COVID-19 Source Type: research
Paediatr Anaesth. 2021 Dec 19. doi: 10.1111/pan.14382. Online ahead of print.ABSTRACTNeonatal and childhood infectious diseases continue to be a global health problem. Acute respiratory tract infections are typically classified as upper respiratory tract infection and lower respiratory tract infections. The most common lower respiratory infections in childhood are pneumonia and bronchiolitis. Vaccination against measles, diphtheria, pertussis, Haemophilus influenzae, pneumococcus, and influenza resulted in a significant reduction in the incidence of acute respiratory tract infection globally. Though the global burden of th...
Source: Paediatric Anaesthesia - Category: Anesthesiology Authors: Source Type: research
e van Baarle Consensus on timing of post-hematopoietic stem cell transplantation (HSCT) vaccination is currently lacking and is therefore assessed in this review. PubMed was searched systematically for articles concerning vaccination post-HSCT and included a basis in predefined criteria. To enable comparison, data were extracted and tables were constructed per vaccine, displaying vaccine response as either seroprotection or seroconversion for allogeneic HSCT (alloHSCT) and autologous HSCT (autoHSCT) separately. A total of 33 studies were included with 1914 patients in total: 1654 alloHSCT recipients and 260 autoHSCT re...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
Expert Rev Anti Infect Ther. 2021 Dec 2. doi: 10.1080/14787210.2022.2013808. Online ahead of print.ABSTRACTINTRODUCTION: In solid organ transplant (SOT) recipients, viral infections are associated with direct morbidity and mortality and may influence long-term allograft outcomes. Prevention of viral infections by vaccination, antiviral prophylaxis, and behavioral measures is therefore of paramount importance.AREAS COVERED: We searched Pubmed to select publications to review current preventive strategies against the most important viral infections in SOT recipients, including SARS-CoV-2, influenza, CMV and other herpesvirus...
Source: Expert Review of Anti-Infective Therapy - Category: Infectious Diseases Authors: Source Type: research
CONCLUSION: The Swiss dental healthcare workers participating in this study had a medium level of awareness towards vaccinations. Almost all participants were vaccinated against HBV, but they were particularly hesitant about the seasonal influenza vaccination. As a considerable number of participants was unaware of their immunisation status, more comprehensive information on infectious diseases, vaccination and prevention is essential.PMID:34794273 | DOI:10.4414/SMW.2021.w30036
Source: Swiss Medical Weekly - Category: General Medicine Authors: Source Type: research
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