Penn study paves way for new vaccines to protect infants against infections

(University of Pennsylvania School of Medicine) A new Penn Medicine study puts researchers within closer reach of vaccines that can protect infants against infections by overcoming a mother's antibodies, which are known to shut down immune defenses initiated by conventional vaccines. That hurdle largely explains why vaccinations for infectious diseases like influenza and measles not given until six to 12 months of age. Findings from the preclinical study were published online today in Science Translational Medicine.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news

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MMWR Morb Mortal Wkly Rep. 2021 Oct 15;70(41):1435-1440. doi: 10.15585/mmwr.mm7041a1.ABSTRACTImmunization is a safe and cost-effective means of preventing illness in young children and interrupting disease transmission within the community.* The Advisory Committee on Immunization Practices (ACIP) recommends vaccination of children against 14 diseases during the first 24 months of life (1). CDC uses National Immunization Survey-Child (NIS-Child) data to monitor routine coverage with ACIP-recommended vaccines in the United States at the national, regional, state, territorial, and selected local levels.† CDC assessed v...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Source Type: research
ConclusionAdherence to STIKO recommendations was poor. However, patients are willing to follow a physician ’s recommendation for vaccination.
Source: Infection - Category: Infectious Diseases Source Type: research
CONCLUSIONS: We have developed a transparent, evidence-based rigorous framework to defined key research questions to generate evidence towards the design of policies and strategies to increase vaccine coverage. Results were disseminated broadly and submitted to the EC for potential funding in the context of The Horizon Europe Program. The same process will be conducted in 2021 to identify vaccination research priorities regarding all vaccines used in the EU as well as COVID-19 vaccines.PMID:34598823 | DOI:10.1016/j.vaccine.2021.09.033
Source: Vaccine - Category: Allergy & Immunology Authors: Source Type: research
CONCLUSION: This study indicates that the broader group of immigrants, and in particular refugees and asylum seekers, do not represent a homogenous group in terms of immunisation coverage, and that each cohort should be carefully considered during immunisation interventions and strategies. This will be particularly important during targeted health promotions and future immunisation programs in this cohort.PMID:34556368 | DOI:10.1016/j.vaccine.2021.09.026
Source: Vaccine - Category: Allergy & Immunology Authors: Source Type: research
This study includes a retrospective cohort of pregnancies in women aged 12-55 years resulting in live birth, spontaneous abortion, or stillbirth identified in the IBM® MarketScan® Commercial, Blue Health Intelligence® (BHI®) Commercial, and IBM MarketScan Multi-State Medicaid Databases from August 1, 2016, to December 31, 2018. Gestational age at vaccination was determined using a validated algorithm. We examined vaccines (1) recommended by the Centers for Disease Control and Prevention Advisory Committee on Immunization Practices (ACIP) (tetanus, diphtheria, and acellular pertussis [Tdap]; inactivated infl...
Source: Vaccine - Category: Allergy & Immunology Authors: Source Type: research
[The Conversation Africa] Vaccines have long been an integral part of public health programmes around the world, reducing the spread and severity of infectious diseases. The success of immunisation strategies to protect children from diseases like polio, hepatitis B, and measles, and adults from influenza and pneumococcal disease, can be seen globally.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
rshburg Diseases caused by human herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) affect millions of people worldwide and range from fatal encephalitis in neonates and herpes keratitis to orofacial and genital herpes, among other manifestations. The viruses can be shed efficiently by asymptomatic carriers, causing increased rates of infection. Viral transmission occurs through direct contact of mucosal surfaces followed by initial replication of the incoming virus in skin tissues. Subsequently, the viruses infect sensory neurons in the trigeminal and lumbosacral dorsal root ganglia, where they are primarily maintai...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
Curr Opin Immunol. 2021 Jun 9;71:62-68. doi: 10.1016/j.coi.2021.05.009. Online ahead of print.ABSTRACTBy refusing or delaying vaccination, vaccine hesitant individuals and communities undermine the prevention, and ultimately, elimination of communicable diseases against which safe and effective vaccines are available. We reviewed recent evidence of vaccine hesitancy within migrant communities in the context of increased human mobility and widespread anti-immigrant sentiment and manifest xenophobia. Among many immigrant parents and families, vaccine hesitancy is largely associated with fears and misinformation about vaccine...
Source: Current Opinion in Immunology - Category: Allergy & Immunology Authors: Source Type: research
CONCLUSIONS: Across a large body of research we found few associations of vaccines and serious key adverse events; however, rare events are challenging to study. Any adverse events should be weighed against the protective benefits that vaccines provide.PMID:34049735 | DOI:10.1016/j.vaccine.2021.03.079
Source: Vaccine - Category: Allergy & Immunology Authors: Source Type: research
Tsakris Earthquake-induced tsunamis have the potential to cause extensive damage to natural and built environments and are often associated with fatalities, injuries, and infectious disease outbreaks. This review aims to examine the occurrence of respiratory infections (RIs) and to elucidate the risk factors of RI transmission following tsunamis which were induced by earthquakes in the last 20 years. Forty-seven articles were included in this review and referred to the RIs emergence following the 2004 Sumatra-Andaman, the 2009 Samoa, and the 2011 Japan earthquakes. Polymicrobial RIs were commonly detected among near-d...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Review Source Type: research
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