Smoking cessation and weight change in relation to cardiovascular disease incidence and mortality in people with type 2 diabetes: a population-based cohort study

Publication date: Available online 7 January 2020Source: The Lancet Diabetes & EndocrinologyAuthor(s): Gang Liu, Yang Hu, Geng Zong, An Pan, JoAnn E Manson, Kathryn M Rexrode, Eric B Rimm, Frank B Hu, Qi SunSummaryBackgroundTo reduce their overall substantially increased risk of cardiovascular disease and premature mortality, smoking cessation is especially important for people with diabetes. However, the effect of weight change after quitting smoking on the long-term health consequences of smoking cessation is unclear. We aimed to examine smoking cessation and subsequent weight change in relation to incident cardiovascular disease events and mortality among adults with type 2 diabetes.MethodsIn this population-based cohort study, we analysed data from people with type 2 diabetes from two prospective cohorts in the USA: the Nurses' Health Study (1976–2014) and the Health Professionals Follow-Up Study (1986–2014). We included participants from both cohorts who either had prevalent type 2 diabetes or were diagnosed during the study, and who were either current smokers or never smokers without cardiovascular disease or cancer at diagnosis of diabetes. Information on demographics, newly diagnosed diseases, medical history, and lifestyle factors, including smoking status and weight change, was updated every 2 years through validated questionnaires. We assessed the incidence of cardiovascular disease and all-cause and cause-specific mortality among recent quitters (within 6 yea...
Source: The Lancet Diabetes and Endocrinology - Category: Endocrinology Source Type: research