Acute whole apple consumption did not influence postprandial lipemia: A randomized crossover trial.

This study aimed to explore the effects of whole apple consumption on PPL, as a risk factor for cardiovascular diseases, in generally healthy but overweight and obese adults. A randomized, crossover acute meal trial was conducted with 17 women and 9 men (mean body mass index of 34.1 (SEM 0.2) kg/m2). Blood samples were collected for 6 hours after participants consumed an oral fat tolerance test meal that provided 1 g fat/kg body weight and 1500 mg acetaminophen per meal for estimating gastric emptying, with and without three whole raw Gala apples (~200 g). Plasma triacylglycerol (TAG, with peak postprandial concentration as the primary outcome), apolipoprotein B-48 (apoB48), chylomicron-rich fraction (CMRF) particle size and fatty acid composition, glucose, insulin and acetaminophen were analyzed. Differences between with and without apples were identified by analysis of covariance. Apple consumption did not alter postprandial TAG response, chylomicron properties, glucose or acetaminophen (P>0.05), but did lead to a higher apoB48 peak concentration and exaggerated insulin between 20-180 min (P<0.05). Overall, as a complex food matrix, apples did not modulate postprandial TAG when consumed with a high fat meal in overweight and obese adults, but did stimulate insulin secretion, potentially contributing to increased TAG-rich lipoprotein production. PMID: 31902373 [PubMed - as supplied by publisher]
Source: The British Journal of Nutrition - Category: Nutrition Authors: Tags: Br J Nutr Source Type: research