Gotfried positive reduction promotes the repair of femoral neck fracture potentially via enhancing osteogenesis and angiogenesis.

Gotfried positive reduction promotes the repair of femoral neck fracture potentially via enhancing osteogenesis and angiogenesis. Biomed Pharmacother. 2020 Jan 02;123:109801 Authors: Wang G, Wang B, Wu X, Yang H Abstract The aim of this study was to investigate the effect of Gotfried positive reduction (GPR) on repair of femoral neck fracture in rabbits and its underlying mechanisms. Male New Zealand white rabbits were employed to establish the model of femoral neck fracture. All the rabbits were randomly divided into four groups: control, open accurate reduction (OR), closed Gotfried negative support reduction (CR-N) and closed Gotfried positive support reduction (CR-P). At the 8th and 12th week after surgery, the anteroposterior and lateral radiographs of their hip joints were taken by X-ray, and local hemodynamics of their hip joints was detected by ultrasound. Histological examination was evaluated by HE staining and bone biological strength test was measured by testing machine, which was performed to study the repair of femoral neck fracture. Osteogenesis and angiogenesis-related proteins were measured by western blot in bone tissues and synovial tissues. The results revealed that the fracture healing intensity and blood supply in CR-P were better than those in CR-N and much more excellent than those in OR. In addition, the content of bone morphogenetic protein2 (BMP2), platelet derived growth factor (PDGF) and ocsteocalcin was higher in CR-P group ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - Category: Drugs & Pharmacology Authors: Tags: Biomed Pharmacother Source Type: research

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Publication date: March 2020Source: Biomedicine &Pharmacotherapy, Volume 123Author(s): Gang Wang, Bin Wang, Xuhua Wu, Huilin YangAbstractThe aim of this study was to investigate the effect of Gotfried positive reduction (GPR) on repair of femoral neck fracture in rabbits and its underlying mechanisms. Male New Zealand white rabbits were employed to establish the model of femoral neck fracture. All the rabbits were randomly divided into four groups: control, open accurate reduction (OR), closed Gotfried negative support reduction (CR-N) and closed Gotfried positive support reduction (CR-P). At the 8th and 12th week afte...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
​Subungual hematomas can be a terror. They are painful, ugly-looking, nefarious, and sometimes confusing. The ultimate goal is to drain the accumulated blood and relieve the painful pressure.The best intervention is easy and straightforward: Leave the nail in place, and evacuate the blood under it. (Hand Surg. 2012;17[1]:151; Am J Emerg Med. 2006;24[7]:875; Emerg Med J. 2003;20[1]:65, http://bit.ly/2mHV1cO.) Then, provide excellent discharge information without prescribing antibiotics.A subungual hematoma in a 21-year-old man who slammed his thumb in a car door about 12 hours before ED arrival. Photo by M. Roberts.Distal...
Source: The Procedural Pause - Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
ConclusionThere are numerous reports of the minimally invasive repair of CSD; however, it remains unknown in the obstetrical literature when interventions are required. Patients with minimal myometrial thinning and without evidence of serosal dehiscence may not require repair of the defect. More evidence is needed to observe obstetrical outcomes with or without repair.
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
The objective of this study was to evaluate the use of piezosurgery for osteotomy and odontosection in the repair of the alveoli four months after exodontia. Fifteen young patients who needed third molars extracted were included. During the extractions, one of the teeth was included in the Piezo group, in which ultrasound motor tips were used in both procedures. The other tooth was removed with a conventional rotary instrument. The values of density of the repair regions of the right and left third molars were compared using digital panoramic radiographs. There were no significant differences (p > 0.05): piezo...
Source: British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Source Type: research
This study indicates that augmentation of large rotator cuff repairs with a GraftJacket® scaffold is a viable option and has good functional results and sustained viability.Level of evidenceLevel 4.
Source: Journal of Clinical Orthopaedics and Trauma - Category: Orthopaedics Source Type: research
​BY ALI OZCAN, MD; AYUSH GUPTA, MD; ISABEL NEACATO, MD; DAVID DONALDSON, DO; &SHANNA JONES, MDA 17-year-old boy presented to the pediatric emergency department complaining of a right shoulder injury and right clavicular pain for two hours. The pain started after he checked another player into the boards while playing hockey. He had no head injury, loss of consciousness, or other trauma. He took 600 mg of ibuprofen with no relief, so he came to the ED.He had no past medical or surgical problems, and reported his pain as 4/10 over the clavicle region. His review of system was otherwise negative. The patient's vitals we...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
Publication date: May 2019Source: Journal of the American College of Radiology, Volume 16, Issue 5, SupplementAuthor(s): Expert Panel on Vascular Imaging:, Michael Collard, Patrick D. Sutphin, Sanjeeva P. Kalva, Bill S. Majdalany, Jeremy D. Collins, Jens Eldrup-Jorgensen, Christopher J. Francois, Suvranu Ganguli, Andrew J. Gunn, A. Tuba Kendi, Minhajuddin S. Khaja, Piotr Obara, Stephen P. Reis, Kanupriya Vijay, Karin E. DillAbstractAbdominal aortic aneurysm (AAA) is defined as aneurysmal dilation of the abdominal aorta to 3 cm or greater. A high degree of morbidity and mortality is associated with AAA rupture, and imaging ...
Source: Journal of the American College of Radiology - Category: Radiology Source Type: research
Abdominal aortic aneurysm (AAA) is defined as aneurysmal dilation of the abdominal aorta to 3 cm or greater. A high degree of morbidity and mortality is associated with AAA rupture, and imaging surveillance plays an essential role in mitigating the risk of rupture. Aneurysm size and growth rate are factors associated with the risk of rupture, thus surveillance imaging studies must be accurate and reproducible to characterize aneurysm size. Ultrasound, CT angiography, and MR angiography provide an accurate and reproducible assessment of size, while radiographs and aortography provide limited evaluation.
Source: Journal of the American College of Radiology : JACR - Category: Radiology Authors: Tags: Appropriate use criteria Source Type: research
Mark E. Gray1,2*, James Meehan2,3, Paul Sullivan4, Jamie R. K. Marland4, Stephen N. Greenhalgh1, Rachael Gregson1, Richard Eddie Clutton1, Carol Ward2, Chris Cousens5, David J. Griffiths5, Alan Murray4 and David Argyle1 1The Royal (Dick) School of Veterinary Studies and Roslin Institute, University of Edinburgh, Edinburgh, United Kingdom 2Cancer Research UK Edinburgh Centre and Division of Pathology Laboratories, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom 3School of Engineering and Physical Sciences, Institute of Sensors, Signals and Systems, Heriot-Watt Univer...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
Discussion Respiratory problems in infants can caused by many things including any type of obstruction from the nose to lung. Neonates and infants are particularly susceptible to changes in the size of the airway because of the physics of airflow resistance. Important reminders about infant airways: Resistance = 1/radius4 (Poiseuille’s equation) therefore even a 1 mm decrease in the airway circumferences increases the airflow resistance x16. Increased airflow causes less pressure along the walls, which can lead to collapse of the walls (Bernoulli’s and Venturi effects). Neonates have smaller lungs relative to ...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
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