Classical complement cascade initiating C1q protein within neurons in the aged rhesus macaque dorsolateral prefrontal cortex

Cognitive impairment in schizophrenia, aging, and Alzheimer ’s disease is associated with spine and synapse loss from the dorsolateral prefrontal cortex (dlPFC) layer III. Complement cascade signaling is critic...

Source: Journal of Neuroinflammation - January 6, 2020 Category: Neurology Authors: Dibyadeep Datta, Shannon N. Leslie, Yury M. Morozov, Alvaro Duque, Pasko Rakic, Christopher H. van Dyck, Angus C. Nairn and Amy F. T. Arnsten Tags: Research Source Type: research