Local fungus-specific Immunoglobulin E production in chronic rhinosinusitis with nasal polyps.

CONCLUSIONS: Fungus-specific IgEs were highly detectable in NPs of CRSwNP patients, and NPs comprised a major region of specific IgE production. Fungi may therefore play an important role in CRSwNP pathogenesis by inducing Th2 immune responses, including IgE synthesis.
PMID: 31904030 [PubMed - as supplied by publisher]

Source: Rhinology - January 7, 2020 Category: ENT & OMF Tags: Rhinology Source Type: research