Adverse outcomes of proton pump inhibitors in chronic liver disease: a systematic review and meta-analysis

ConclusionsThis study identifies a significant relationship between PPIs therapies and several specific adverse clinical outcomes in CLD. However, these results should be carefully considered given the potential selection bias and unmeasured confounding variables in observational studies, it may be reasonable to re-evaluate the need for PPIs in patients with CLD.

http://link.springer.com/10.1007/s12072-019-10010-3

Source: Hepatology International - January 6, 2020 Category: Infectious Diseases Source Type: research