A new abietane diterpene and anti-complementary constituents from Juniperus tibetica.

A new abietane diterpene and anti-complementary constituents from Juniperus tibetica.
Nat Prod Res. 2020 Jan 05;:1-8
Authors: Zeng DL, Wang CY, Gao HQ, Chen DF, Lu Y
Abstract
Anti-complementary activity-guided fractionation led to the isolation of a new abietane diterpene (1) and twenty-five known compounds (2-26) from the twigs and leaves of Juniperus tibetica. All the compounds were isolated from J. tibetica for the first time. The structure of 1 was assigned by spectroscopic data and X-ray crystallography analysis. Five lignans (2, 3, 7, 9 and 10), two flavones (19 and 22), and one coumarin (23) exhibited anti-complementary activity with CH50 values ranging from 0.3 to 3.69 mM.
PMID: 31903783 [PubMed - as supplied by publisher]

Source: Natural Product Research - January 4, 2020 Category: Biochemistry Authors: Zeng DL, Wang CY, Gao HQ, Chen DF, Lu Y Tags: Nat Prod Res Source Type: research