Is Schizophrenia a Neurodegenerative Disease? Evidence from Age-Related Decline of Brain-Derived Neurotrophic Factor in the Brains of Schizophrenia Patients and Matched Nonpsychiatric Controls.

Conclusion: PFC BDNF does not follow a normative linear age effect in schizophrenia patients as they grow older, which may represent a 'floor effect' due to earlier decline or a survivor cohort of older patient donors who are less susceptible to a schizophrenia-related pathological aging process. © 2014 S. Karger AG, Basel. PMID: 25531449 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/25531449?dopt=Abstract

Source: Neuro-Degenerative Diseases - December 17, 2014 Category: Neurology Authors: Rao J, Chiappelli J, Kochunov P, Regenold WT, Rapoport SI, Hong LE Tags: Neurodegener Dis Source Type: research

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